TRAIL-R1 to -R4 Flow Cytometry Pack Reference: AG-44B-0004 TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Genotyping Kit Reference: 2GTK-100 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
Genotyping Kit Reference: 2GTK-250 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
Genotyping Kit Reference: 2GTK-500 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
One-step DNA Library Prep Kit for Illumina (1 ng Input DNA) Reference: K1255-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (1 ng Input DNA) Reference: K1255-96 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (5 ng Input DNA) Reference: K1256-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (5 ng Input DNA) Reference: K1256-96 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (for 50 ng DNA) Reference: K1257-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (for 50 ng DNA) Reference: K1257-96 Direct and rapid library construction of purified DNA samples by transposase
DNA Library Quantification Kit for Illumina Reference: K1258-500 suitable for DNA libraries quantification for Illumina using the dye qPCR method.
Caspase-8, 10 Activity Fluorometric Assay Kit Reference: RP10238K Caspase-8, 10 Activity Fluorometric Assay Kit can be used for assaying caspase-8, 10, 3, 7 activities in cell/tissue extracts in a 96-well plate format. Each of the supplied fluorogenic substrate and the pan caspase inhibitor Z-VAD-FMK are sufficient for 250 x 100 μl reactions. The supplied TRAIL-treated cell lysate is used as a positive control, sufficient for 5 X 100 μl reactions.