TRAIL-R1 to -R4 Flow Cytometry Pack Reference: AG-44B-0004 TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Genotyping Kit Reference: 2GTK-100 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
Genotyping Kit Reference: 2GTK-250 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
Genotyping Kit Reference: 2GTK-500 DNA Extraction: A fast, easy, single tube lysis, producing quality, PCR ready, DNA in 15 minutes. Amplification: Using Microzone’s 2x MegaMix-GT PCR Mastermix that includes an enhanced PCR reaction buffer, dNTPs and an inert blue loading dye to enable direct gel loading post PCR. Suitable for all templates including GC rich. Enough DNA for numerous typings.
Acetyltransferase Assay Buffer Reference: A01-09-01 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-05 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-20 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-01 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-05 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-20 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
ATP Stock Solution Reference: A50-09-200 10 mM ATP Stock Solution used for preparing hot ATP assay cocktail.