TRAIL-R1 to -R4 Flow Cytometry Pack Reference: AG-44B-0004 TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
One-step DNA Library Prep Kit for Illumina (1 ng Input DNA) Reference: K1255-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (1 ng Input DNA) Reference: K1255-96 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (5 ng Input DNA) Reference: K1256-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (5 ng Input DNA) Reference: K1256-96 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (for 50 ng DNA) Reference: K1257-24 Direct and rapid library construction of purified DNA samples by transposase
One-step DNA Library Prep Kit for Illumina (for 50 ng DNA) Reference: K1257-96 Direct and rapid library construction of purified DNA samples by transposase
DNA Library Quantification Kit for Illumina Reference: K1258-500 suitable for DNA libraries quantification for Illumina using the dye qPCR method.
TrkB (pS478) Positive Control Cell Lysate (Mouse NSC-34)-50 µg Reference: CL-2107-50 This cell lysate is suitable as positive control for Western Blotting, to confirm TrkB phosphorylation at amino acid S478 (rat/mouse) or S479 (human), respectively, using TrkB (pS478/479) rabbit antibody R-1718-50. It is particular useful for complex Western Blotting samples to identify TrkB (pS478/479) immunoreactive bands. This lysate has been prepared by triggering TrkB phosphorylation in retinoic acid-treated mouse NSC34 cells with mature BDNF, and subsequent processing with RIPA buffer. The cell lysate is provided lyophilised for extended stability.
Acetyltransferase Assay Buffer Reference: A01-09-01 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-05 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-20 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).