Category: Reagents

Reference: 9001799-10
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An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001799-25
€0.00 (tax incl.)
An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001799-5
€0.00 (tax incl.)
An inhibitor of ALK5, ALK4, and ALK7 (IC50s = 12, 45, and 7.5 nM, respectively); blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition; used to reprogram fibroblasts...
Reference: 9001800-1
€0.00 (tax incl.)
A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001800-5
€0.00 (tax incl.)
A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001800-500
€0.00 (tax incl.)
A metabolite of vardenafil that is formed by the action of CYP3A4 and CYP3A5
Reference: 9001820-10
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An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-100
€0.00 (tax incl.)
An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-5
€0.00 (tax incl.)
An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001820-50
€0.00 (tax incl.)
An antiepileptic agent; binds to the synaptic vesicle protein SV2A (IC50 = 1.99 μM); suppresses seizures in fully kindled rats
Reference: 9001827-50
€0.00 (tax incl.)
This small molecule library contains molecules that are known either to induce differentiation, to maintain self-renewal and proliferation, or to improve the reprogramming efficiency of various stem cell populations.
Reference: 9001839-1
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Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-10
€0.00 (tax incl.)
Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-25
€0.00 (tax incl.)
Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001839-5
€0.00 (tax incl.)
Promotes the reprogramming of human somatic cells to pluripotent stem cells; increases the number of human foreskin fibroblasts that express alkaline phosphatase when used at 10 μM with four standard reprogramming...
Reference: 9001845-10
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A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001845-25
€0.00 (tax incl.)
A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001845-5
€0.00 (tax incl.)
A monounsaturated fatty acid; one of the primary fatty acids in human skin; levels are increased in isolated sebum from the face and back of patients with acne; levels are decreased in the non-lesional skin and...
Reference: 9001873-100
€0.00 (tax incl.)
A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001873-25
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A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001873-50
€0.00 (tax incl.)
A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of...
Reference: 9001879-1
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An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-10
€0.00 (tax incl.)
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-5
€0.00 (tax incl.)
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001879-50
€0.00 (tax incl.)
An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either...
Reference: 9001881-10
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A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-25
€0.00 (tax incl.)
A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-5
€0.00 (tax incl.)
A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001881-50
€0.00 (tax incl.)
A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)
Reference: 9001893-10
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An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-25
€0.00 (tax incl.)
An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-5
€0.00 (tax incl.)
An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001893-50
€0.00 (tax incl.)
An HIV protease inhibitor (Kis = 0.12 and 1 and HIV-2 protease, respectively) that exhibits antiviral activity with low cytotoxicity
Reference: 9001902-1
€0.00 (tax incl.)
A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001902-5
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A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001902-500
€0.00 (tax incl.)
A precursor in the biosynthesis of porphyrins; used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases; also used in fluorescence-based identification of tumor tissue for...
Reference: 9001920-1
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-10
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-25
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001920-5
€0.00 (tax incl.)
A quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively)
Reference: 9001925-500
€0.00 (tax incl.)
An antagonist of the vitamin D receptor; inhibits VDR-mediated target gene activation at 300 and 1,000 nM in reporter assays; decreases MacCM-induced secretion of IL-1β, IL-6, IL-8, CCL2, and RANTES in preadipocytes...
Reference: 9001935-1
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A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001935-10
€0.00 (tax incl.)
A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001935-5
€0.00 (tax incl.)
A more stable form of (+)-blebbistatin, the inactive form of blebbistatin; has the same stereochemistry as the inactive (+)-blebbistatin enantiomer
Reference: 9001937-100
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A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions
Reference: 9001937-25
€0.00 (tax incl.)
A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions
Reference: 9001937-50
€0.00 (tax incl.)
A form of 12(S)-HETE with an ω-terminal alkyne for use in click chemistry reactions
Reference: 9001949-1
€0.00 (tax incl.)
A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001949-10
€0.00 (tax incl.)
A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001949-5
€0.00 (tax incl.)
A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001962-1
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A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9001962-10
€0.00 (tax incl.)
A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9001962-5
€0.00 (tax incl.)
A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9002002-1
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A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-10
€0.00 (tax incl.)
A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-5
€0.00 (tax incl.)
A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-50
€0.00 (tax incl.)
A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002008-1
€0.00 (tax incl.)
A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002008-10
€0.00 (tax incl.)
A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002008-500
€0.00 (tax incl.)
A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002009-1
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A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-10
€0.00 (tax incl.)
A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-25
€0.00 (tax incl.)
A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-5
€0.00 (tax incl.)
A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002014-10
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A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002014-25
€0.00 (tax incl.)
A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002014-50
€0.00 (tax incl.)
A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002040-10
€0.00 (tax incl.)
A mixture of cyclohexadepsipeptides commonly isolated from fungi that act as ionophores, forming pores in cellular membranes to allow selective ion transport; exhibits antimicrobial activity against a variety of...
Reference: 9002040-50
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A mixture of cyclohexadepsipeptides commonly isolated from fungi that act as ionophores, forming pores in cellular membranes to allow selective ion transport; exhibits antimicrobial activity against a variety of...
Reference: 9002056-1
€0.00 (tax incl.)
A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-100
€0.00 (tax incl.)
A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-50
€0.00 (tax incl.)
A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-500
€0.00 (tax incl.)
A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002067-1
€0.00 (tax incl.)
A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-10
€0.00 (tax incl.)
A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-25
€0.00 (tax incl.)
A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-5
€0.00 (tax incl.)
A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002073-1
€0.00 (tax incl.)
A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-10
€0.00 (tax incl.)
A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-25
€0.00 (tax incl.)
A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-5
€0.00 (tax incl.)
A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002129-10
€0.00 (tax incl.)
A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-25
€0.00 (tax incl.)
A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-5
€0.00 (tax incl.)
A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-50
€0.00 (tax incl.)
A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002140-1
€0.00 (tax incl.)
A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-10
€0.00 (tax incl.)
A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-5
€0.00 (tax incl.)
A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-50
€0.00 (tax incl.)
A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002172-25
€0.00 (tax incl.)
A macrolide antibiotic that shows good bactericidal activity against MRSA
Reference: 9002172-5
€0.00 (tax incl.)
A macrolide antibiotic that shows good bactericidal activity against MRSA

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