Category: Reagents

Reference: 9000760-500
€0.00 (tax incl.)
An inhibitor of microtubule polymerization (IC50 = 3.2 µM); inhibits growth of MCF-7 human breast carcinoma cells (IC50 = 13 nM); inhibits neutrophil motility and activity when used at a dose of 5 µmol/kg in a mouse...
Reference: 9000783-1
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000783-10
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000783-5
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000784-1
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000784-10
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000784-5
€0.00 (tax incl.)
An enantiomer of C75, which in racemic form is a stable FASN inhibitor that when administered leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice
Reference: 9000785-1
€0.00 (tax incl.)
An inhibitor of SAH hydrolase (Ki = 3.9 μM); has anti-inflammatory, antiviral, and antibacterial activities
Reference: 9000785-10
€0.00 (tax incl.)
An inhibitor of SAH hydrolase (Ki = 3.9 μM); has anti-inflammatory, antiviral, and antibacterial activities
Reference: 9000785-5
€0.00 (tax incl.)
An inhibitor of SAH hydrolase (Ki = 3.9 μM); has anti-inflammatory, antiviral, and antibacterial activities
Reference: 9000786-1
€0.00 (tax incl.)
Strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM; can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function
Reference: 9000786-10
€0.00 (tax incl.)
Strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM; can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function
Reference: 9000786-25
€0.00 (tax incl.)
Strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM; can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function
Reference: 9000786-5
€0.00 (tax incl.)
Strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM; can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function
Reference: 9000787-1
€0.00 (tax incl.)
A stable analog of adenosine that acts as an agonist for adenosine receptors (Ki = 0.3, 0.08, 25.5, and 1.9 μM for A1, A2A, A2B, and A3 receptors, respectively); modulates neurotransmission release and blocks seizures...
Reference: 9000787-10
€0.00 (tax incl.)
A stable analog of adenosine that acts as an agonist for adenosine receptors (Ki = 0.3, 0.08, 25.5, and 1.9 μM for A1, A2A, A2B, and A3 receptors, respectively); modulates neurotransmission release and blocks seizures...
Reference: 9000787-5
€0.00 (tax incl.)
A stable analog of adenosine that acts as an agonist for adenosine receptors (Ki = 0.3, 0.08, 25.5, and 1.9 μM for A1, A2A, A2B, and A3 receptors, respectively); modulates neurotransmission release and blocks seizures...
Reference: 9000890-1
€0.00 (tax incl.)
An inactive derivative of KN-93, the selective inhibitor of CaMKII; ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts at concentrations up to 25 μM
Reference: 9000890-10
€0.00 (tax incl.)
An inactive derivative of KN-93, the selective inhibitor of CaMKII; ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts at concentrations up to 25 μM
Reference: 9000890-5
€0.00 (tax incl.)
An inactive derivative of KN-93, the selective inhibitor of CaMKII; ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts at concentrations up to 25 μM
Reference: 9000891-1
€0.00 (tax incl.)
A photoaffinity probe that consists of active progesterone, a diazirine-UV (312 nm)-sensitive moiety, and a biotin tag; can be used to detect and observe the interaction of progesterone with target proteins
Reference: 9000891-5
€0.00 (tax incl.)
A photoaffinity probe that consists of active progesterone, a diazirine-UV (312 nm)-sensitive moiety, and a biotin tag; can be used to detect and observe the interaction of progesterone with target proteins
Reference: 9000891-500
€0.00 (tax incl.)
A photoaffinity probe that consists of active progesterone, a diazirine-UV (312 nm)-sensitive moiety, and a biotin tag; can be used to detect and observe the interaction of progesterone with target proteins
Reference: 9000939-10
€0.00 (tax incl.)
An acylcarnitine formed from carnitine conjugated to arachidonic acid; may be useful as a marker of mitochondrial dysfunction
Reference: 9000939-25
€0.00 (tax incl.)
An acylcarnitine formed from carnitine conjugated to arachidonic acid; may be useful as a marker of mitochondrial dysfunction
Reference: 9000939-50
€0.00 (tax incl.)
An acylcarnitine formed from carnitine conjugated to arachidonic acid; may be useful as a marker of mitochondrial dysfunction
Reference: 9000976-10
€0.00 (tax incl.)
A structural analog of the inhibitory neurotransmitter GABA that irreversibly inhibits its catabolism by GABA transaminase; produces a dose-dependent increase in extracellular GABA, and has been shown to result in...
Reference: 9000976-25
€0.00 (tax incl.)
A structural analog of the inhibitory neurotransmitter GABA that irreversibly inhibits its catabolism by GABA transaminase; produces a dose-dependent increase in extracellular GABA, and has been shown to result in...
Reference: 9000976-5
€0.00 (tax incl.)
A structural analog of the inhibitory neurotransmitter GABA that irreversibly inhibits its catabolism by GABA transaminase; produces a dose-dependent increase in extracellular GABA, and has been shown to result in...
Reference: 9000976-50
€0.00 (tax incl.)
A structural analog of the inhibitory neurotransmitter GABA that irreversibly inhibits its catabolism by GABA transaminase; produces a dose-dependent increase in extracellular GABA, and has been shown to result in...
Reference: 9000980-1
€0.00 (tax incl.)
An orally active inhibitor of PI3-kinase γ that suppresses joint inflammation in mouse models of rheumatoid arthritis; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8,...
Reference: 9000980-10
€0.00 (tax incl.)
An orally active inhibitor of PI3-kinase γ that suppresses joint inflammation in mouse models of rheumatoid arthritis; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8,...
Reference: 9000980-25
€0.00 (tax incl.)
An orally active inhibitor of PI3-kinase γ that suppresses joint inflammation in mouse models of rheumatoid arthritis; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8,...
Reference: 9000980-5
€0.00 (tax incl.)
An orally active inhibitor of PI3-kinase γ that suppresses joint inflammation in mouse models of rheumatoid arthritis; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8,...
Reference: 9000988-1
€0.00 (tax incl.)
A pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM); also potently inhibits c-src (IC50 = 6 nM); effectively blocks...
Reference: 9000988-10
€0.00 (tax incl.)
A pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM); also potently inhibits c-src (IC50 = 6 nM); effectively blocks...
Reference: 9000988-5
€0.00 (tax incl.)
A pyridopyrimidine-type inhibitor of receptor tyrosine kinases that inhibits c-abl (IC50 = 8 nM) and Bcr/Abl-dependent cell growth (IC50 = 0.4 nM); also potently inhibits c-src (IC50 = 6 nM); effectively blocks...
Reference: 9001147-1
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; produced via lactonolysis from 3-oxodecanoyl-homoserine lactone
Reference: 9001147-10
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; produced via lactonolysis from 3-oxodecanoyl-homoserine lactone
Reference: 9001147-5
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; produced via lactonolysis from 3-oxodecanoyl-homoserine lactone
Reference: 9001148-1
€0.00 (tax incl.)
An NSAID and COX inhibitor (IC50s = 20 nM for both COX-1 and COX-2); prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases PGE2 levels in paw tissue in a mouse model...
Reference: 9001148-100
€0.00 (tax incl.)
An NSAID and COX inhibitor (IC50s = 20 nM for both COX-1 and COX-2); prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases PGE2 levels in paw tissue in a mouse model...
Reference: 9001148-50
€0.00 (tax incl.)
An NSAID and COX inhibitor (IC50s = 20 nM for both COX-1 and COX-2); prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases PGE2 levels in paw tissue in a mouse model...
Reference: 9001148-500
€0.00 (tax incl.)
An NSAID and COX inhibitor (IC50s = 20 nM for both COX-1 and COX-2); prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases PGE2 levels in paw tissue in a mouse model...
Reference: 9001150-1
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; can have activating or suppressing effects on gene expression and biofilm formation, respectively; produced via lactonolysis from...
Reference: 9001150-10
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; can have activating or suppressing effects on gene expression and biofilm formation, respectively; produced via lactonolysis from...
Reference: 9001150-25
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; can have activating or suppressing effects on gene expression and biofilm formation, respectively; produced via lactonolysis from...
Reference: 9001150-5
€0.00 (tax incl.)
A small diffusible signaling molecule secreted by various bacteria; can have activating or suppressing effects on gene expression and biofilm formation, respectively; produced via lactonolysis from...
Reference: 9001155-10
€0.00 (tax incl.)
An alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties
Reference: 9001155-25
€0.00 (tax incl.)
An alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties
Reference: 9001155-5
€0.00 (tax incl.)
An alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties
Reference: 9001155-50
€0.00 (tax incl.)
An alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties
Reference: 9001181-10
€0.00 (tax incl.)
An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001181-25
€0.00 (tax incl.)
An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001181-5
€0.00 (tax incl.)
An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001181-50
€0.00 (tax incl.)
An imidazole that potently antagonizes the α2-adrenoceptor (Ki = 1.6 nM); shows selectivity over the α1-adrenoceptor (Ki = 13,300 nM) and is a poor antagonist at a wide variety of other receptors and channels
Reference: 9001369-1
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-10
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-25
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001369-5
€0.00 (tax incl.)
A form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry; has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO
Reference: 9001373-25
€0.00 (tax incl.)
A tyramine metabolite; enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50s = 0.13 and 0.48 μg/ml for doxorubicin plus N-acetyltyramine and doxorubicin alone, respectively)
Reference: 9001373-5
€0.00 (tax incl.)
A tyramine metabolite; enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50s = 0.13 and 0.48 μg/ml for doxorubicin plus N-acetyltyramine and doxorubicin alone, respectively)
Reference: 9001475-10
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-100
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-25
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001475-50
€0.00 (tax incl.)
An anionic oligopeptide-based bola-amphiphile that contains a hexane moiety flanked by a glycylglycine group at each end, which creates distinct hydrophilic and hydrophobic regions
Reference: 9001479-5
€0.00 (tax incl.)
A quinone bacterial metabolite; inhibits the growth of a variety of bacteria (MICs = P. falciparum (IC80 = 0.0033 µM); inhibits proliferation of HCT116, A549, and HL-60 cancer cells (IC50s = 0.4, 4.1, and 0.8 µM,...
Reference: 9001510-1
€0.00 (tax incl.)
An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001510-10
€0.00 (tax incl.)
An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001510-5
€0.00 (tax incl.)
An erlotinib analog characterized by the addition of a methyl group at the four position of the phenyl group
Reference: 9001533-1
€0.00 (tax incl.)
An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-10
€0.00 (tax incl.)
An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-25
€0.00 (tax incl.)
An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001533-5
€0.00 (tax incl.)
An isomer of Vitamin E that has less potent antioxidant properties than α-tocotrienol
Reference: 9001535-1
€0.00 (tax incl.)
A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001535-10
€0.00 (tax incl.)
A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001535-5
€0.00 (tax incl.)
A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between...
Reference: 9001536-1
€0.00 (tax incl.)
A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001536-10
€0.00 (tax incl.)
A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001536-5
€0.00 (tax incl.)
A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of...
Reference: 9001577-1
€0.00 (tax incl.)
An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-10
€0.00 (tax incl.)
An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-25
€0.00 (tax incl.)
An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001577-5
€0.00 (tax incl.)
An antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties
Reference: 9001589-1
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-10
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-25
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001589-5
€0.00 (tax incl.)
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for...
Reference: 9001737-1
€0.00 (tax incl.)
A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa
Reference: 9001737-10
€0.00 (tax incl.)
A small diffusible signaling molecule involved in quorum sensing in the model symbiont V. fischeri and the pathogens A. tumefaciens and P. aeruginosa

Menu

Settings