Category: Reagents

Reference: 9001949-1
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A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001949-10
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A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001949-5
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A CB2 receptor agonist; selective for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively),
Reference: 9001962-1
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A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9001962-10
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A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9001962-5
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A selective inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively); absorbed through enterocytes, metabolically stable in human...
Reference: 9002002-1
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A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-10
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A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-5
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A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002002-50
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A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of...
Reference: 9002008-1
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A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002008-10
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A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002008-500
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A β-lactam antibiotic; active against Gram-negative bacteria, including E. coli, K. pneumoniae, and N. gonorrhoeae (MIC90s = 4, 8, and 1 μg/ml, respectively); active against clinical isolates of E. coli, K....
Reference: 9002009-1
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A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-10
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A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-25
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A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002009-5
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A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E. coli, K. pneumonia,...
Reference: 9002014-10
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A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002014-25
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A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002014-50
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A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 with an IC50 value of 350 nM; commonly used to study...
Reference: 9002040-10
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A mixture of cyclohexadepsipeptides commonly isolated from fungi that act as ionophores, forming pores in cellular membranes to allow selective ion transport; exhibits antimicrobial activity against a variety of...
Reference: 9002040-50
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A mixture of cyclohexadepsipeptides commonly isolated from fungi that act as ionophores, forming pores in cellular membranes to allow selective ion transport; exhibits antimicrobial activity against a variety of...
Reference: 9002056-1
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A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-100
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A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-50
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A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002056-500
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A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH...
Reference: 9002067-1
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A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-10
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A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-25
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A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002067-5
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A selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively); used in combination with PD 0325901, CHIR99021, and SB-590885 to support self-renewal of...
Reference: 9002073-1
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A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-10
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A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-25
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A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002073-5
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A photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM
Reference: 9002129-10
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A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-25
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A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-5
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A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002129-50
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A non-selective, low-trapping, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM; used to produce antidepressant effects without adverse...
Reference: 9002140-1
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A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-10
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A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-5
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A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002140-50
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A dual orexin receptor antagonist; reduces locomotor activity and promotes sleep in animal and clinical studies by inhibiting the bind of orexin A and B; decreases self-administration and seeking of cocaine in rats;...
Reference: 9002172-25
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A macrolide antibiotic that shows good bactericidal activity against MRSA
Reference: 9002172-5
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A macrolide antibiotic that shows good bactericidal activity against MRSA
Reference: 9002196-10
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A toxin that selectively eliminates pancreatic β-cells in mice, rats, and certain other animals, and is used to model type 1 diabetes in humans
Reference: 9002196-5
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A toxin that selectively eliminates pancreatic β-cells in mice, rats, and certain other animals, and is used to model type 1 diabetes in humans
Reference: 9002215-1
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A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-10
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A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-5
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A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-500
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A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002267-10
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A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-100
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A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-250
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A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-50
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A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002298-1
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An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-100
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An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-50
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An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-500
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An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002314-1
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A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-10
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A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-5
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A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-500
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A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002339-1
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A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-10
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A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-5
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A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-500
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A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002357-1
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An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-10
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An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-25
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An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-5
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An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002360-1
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A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-10
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A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-5
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A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-500
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A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002394-1
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A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-10
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A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-25
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A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-5
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A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002409-10
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An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-100
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An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-25
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An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-5
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An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002444-1
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A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002444-10
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A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002444-5
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A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002449-10
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A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-25
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A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-5
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A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-50
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A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002461-100
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A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via...
Reference: 9002461-250
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A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via...

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