Terminal α-linked Galactose & N- Acetylgalactosamine (GalNAc) Reference: RPL-αGal Monomer MW: 14,161 Da. Protein is a dimer under physiological conditions (PBS pH7.2).
Terminal β-linked Galactose & N-Acetyllactosamine (LacNAc) Reference: RPL-Gal1 Monomer MW: 14,066 Da. Protein is a dimer under physiological conditions (PBS pH7.2).
Terminal α-linked Galactose Reference: RPL-Gal3 Monomer MW: 14,081 Da. Protein is a tetramer under physiological conditions (PBS pH7.2).
Terminal β-linked Galactose, N-Acetyllactosamine (LacNAc) & Lewis x (Lex) Reference: RPL-Gal4 Monomer MW: 14,595 Da. Protein is a tetramer under physiological conditions (PBS pH7.2).
Fucose/Mannose: Lewis a (Lea), Lewis x (Lex) & terminal a-mannose Reference: RPL-αMan Monomer MW: 13,130 Da Exists as dimer under physiological conditions (PBS, pH7.2).
Terminal α-mannose Reference: RPL-Man2 Monomer MW: 15,163 Da. Exists as a dimer under physiological conditions (PBS, pH7.2).
Terminal α2-3-linked Sialic Acid (Neu5Ac) — on both Nlinked and O-Linked Reference: RPL-Sia1 Monomer MW: 27,407.14 Da. Exists a monomer under physiological conditions (PBS pH7.2).
Terminal α2-3-linked Sialic Acid (Neu5Ac) — on O-Linked Glycans Reference: RPL-Sia2 Monomer MW: 40,725.17 Da. Exists as a monomer under physiological conditions (PBS pH7.2).
Terminal α-linked Neu5Ac Reference: RPL-Sia3 Monomer MW: 19,584.89 Da. Exists as a monomer under physiological conditions (PBS pH7.2).
Active Recombinant Human TNF-alpha Protein Reference: RP00001 Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. KNockout studies in mice also suggested the neuroprotective function of this cytokine.
Active Recombinant Human IL-1 beta Protein Reference: RP00002 Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family.This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity.