Category: Proteins & Peptides

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Reference: GTX57302-pro

OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors (Lan et al., 24 [PubMed 15175245]).[supplied by OMIM, Mar 28]

Reference: GTX57303-pro

DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 18741), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 21 [PubMed 11473582]).[supplied by OMIM, Mar 28]

Reference: GTX57304-pro

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 216]

Reference: HY-P4073

ANG1005 is a brain-penetrating peptide-agent conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system.

Reference: GTX57305-pro

This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked cognitive disability. [provided by RefSeq, Aug 213]

Reference: HY-P0186

Endomorphin 2, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.

Reference: GTX57306-pro

This gene encodes a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17. [provided by RefSeq, Jul 214]

Reference: GTX57307-pro

By binding phosphotyrosines through its free SRC (MIM 199) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 21 [PubMed 11689425]).[supplied by OMIM, Mar 28]