ELA-32(human) TFA Reference: HY-P2196A ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
Gly6 hydrochloride Reference: HY-P0148A Gly6 hydrochloride (Hexaglycine hydrochloride) is a linear glycine oligopeptide with six glycines.
Mouse CXCL1 / GRO Alpha protein (active) Reference: GTX48313-pro This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 213]
Ac-IHIHIQI-NH2 Reference: HY-P4147 Ac-IHIHIQI-NH2 is a fibril-forming heptapeptide with high catalytic activity to laccase mimics. Ac-IHIHIQI-NH2 exhibits selectivity for hydrophobic p-nitrophenyl (ONp) ester substrates in the process of self-assembly.
P60v-src(137-157) Reference: HY-P2372 P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60v-src (IC50: 7.5 μM).
16-38-Thymosin β4 (cattle) Reference: HY-P3965 16-38-Thymosin β4 (cattle) is a Ca2+-independent MLCK activator with high affinity.
IGF-I (24-41) (TFA) Reference: HY-P1777A IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development.