Benzyl (tert-butoxycarbonyl)-L-tyrosinate Reference: HY-W111214 Benzyl (tert-butoxycarbonyl)-L-tyrosinate is a tyrosine derivative.
Human TRAIL protein (active) Reference: GTX01404-pro-S The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF1A/TRAILR1, TNFRSF1B/TRAILR2, TNFRSF1C/TRAILR3, TNFRSF1D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF1C/TRAILR3, TNFRSF1D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 21]
C3a (70-77) (TFA) Reference: HY-P1505A C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.
Human TRAIL protein (active) Reference: GTX01404-pro The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF1A/TRAILR1, TNFRSF1B/TRAILR2, TNFRSF1C/TRAILR3, TNFRSF1D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF1C/TRAILR3, TNFRSF1D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 21]
ReACp53 Reference: HY-P0121 ReACp53 could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.
Human USP7 protein, GST and His tag Reference: GTX01405-pro-S The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 216]
(S)-2-Amino-2-(4-fluorophenyl)acetic acid Reference: HY-W002519 (S)-2-Amino-2-(4-fluorophenyl)acetic acid is a Glycine (HY-Y0966) derivative.
Human USP7 protein, GST and His tag Reference: GTX01405-pro The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 216]
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA Reference: HY-P3480 H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins.
Thioredoxin reductase peptide Reference: HY-P1948 Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense.