Abltide Reference: A02-58-1000 The Abltide peptide sequence (EAIYAAPFAKKK) is based on the C-terminus of Abl.
Rat Interferon gamma protein, His tag (active) Reference: GTX00340-pro an immune molecule produced by T lymphocytes in response to mitogens or antigens [RGD, Feb 26]
Acetylated Histone H3 Peptide I Reference: H12-358-500 The Acetylated Histone H3 (K9, 14) Peptide sequence (ARTKQTAR[Ac-K]STGG[Ac-K]APRKQLAGGKKC) is derived from human histone H3 (1-21) and is suitable for use as the assay control of histone (de-)methylation and (de-) acetylation.
Rat IL6 protein, His tag (active) Reference: GTX00341-pro a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 26]
Acetylated Histone H4 Peptide I Reference: H13-358-500 The Acetylated Histone H4 (K5, 8, 12, 16) Peptide sequence (SGRG[Ac-K]GG[Ac-K]GLG[Ac-K]GGA[Ac-K]RHRKVGGKKC) is derived from human histone H4 (1-21) and is suitable for use as the assay control of histone (de-)methylation and (de-)acetylation.
Rat TNF alpha protein, His tag (active) Reference: GTX00342-pro acts as a cytokine; binds TNF receptors; plays a role in regulation of cell proliferation, induction of apoptosis, and inflammatory response [RGD, Feb 26]
AMARA Peptide Reference: A11-58 The AMARA substrate peptide sequence (AMARAASAAALARRR) is routinely evaluated as a substrate for SIK and AMPK.
Rat VEGFA protein, His tag (active) Reference: GTX00343-pro This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 215]
Autocamtide 2 Reference: A15-58 The Autocamtide 2 peptide sequence (KKALRRQETVDAL-amide) is based on the autophosphorylation site (amino acid 283-290) on CaMKII.
Axltide Reference: A16-58 The Axltide peptide sequence (KKSRGDYMTMQIG) is based on the mouse Insulin receptor substrate 1 (amino acid 979-989).
Rat Endothelin 1 protein, His tag (active) Reference: GTX00345-pro activates ERK1/2 mediated signaling; may play a role in regulation of cardiac contractile force [RGD, Feb 26]