Rat IL1 Receptor 1 protein, His tag Reference: GTX00051-pro receptor for interleukin-1; involved in inflammatory response signalling [RGD, Feb 26]
Syntenin 2 blocking peptide Reference: GTX89753-PEP The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK56 binding protein 1A, 12kDa) gene, as represented in GeneID:152831. [provided by RefSeq, Sep 211]
Rat IL1 Receptor 1 protein, His tag Reference: GTX00052-pro receptor for interleukin-1; involved in inflammatory response signalling [RGD, Feb 26]
Rat IL1 Receptor 1 protein, His tag Reference: GTX00053-pro receptor for interleukin-1; involved in inflammatory response signalling [RGD, Feb 26]
BAF57 blocking peptide Reference: GTX89755-PEP The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 28]
Rat Coagulation factor III/Tissue Factor protein, His tag Reference: GTX00054-pro an initiation factor for blood coagulation; plays a critical role in hepatic ischemic reperfusion injury [RGD, Feb 26]
NEIL1 blocking peptide Reference: GTX89756-PEP This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 212]
Rat Noggin protein, His and MBP tag Reference: GTX00055-pro secreted protein; involved in dorsal fate specification [RGD, Feb 26]
DEF6 blocking peptide Reference: GTX89758-PEP DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 6248) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 23 [PubMed 12923183]).[supplied by OMIM, Mar 28]
Rat Noggin protein, His and GST tag Reference: GTX00056-pro secreted protein; involved in dorsal fate specification [RGD, Feb 26]