TRPV5 blocking peptide Reference: GTX88774-PEP This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 28]
Recombinant Human MCP-3 / CCL7 Reference: GFH131-10 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
IGFBP4 blocking peptide Reference: GTX88775-PEP This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 28]
Recombinant Human MCP-3 / CCL7 Reference: GFH131-100 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
Recombinant Human MCP-3 / CCL7 Reference: GFH131-1000 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
GPR142 blocking peptide Reference: GTX88777-PEP GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 23 [PubMed 1462398]).[supplied by OMIM, Mar 28]
Recombinant Mouse MCP-3 / CCL7 Reference: GFM40-2 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
RASSF3 blocking peptide Reference: GTX88778-PEP The RAS oncogene (MIM 192) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 23]
Recombinant Mouse MCP-3 / CCL7 Reference: GFM40-10 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
ASNA1 blocking peptide Reference: GTX88779-PEP This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 211]
Recombinant Mouse MCP-3 / CCL7 Reference: GFM40-100 Monocyte Chemotactic Protein 3 (MCP-3), also known as CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.