5-HT3B receptor blocking peptide Reference: GTX88391-PEP The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 211]
Recombinant Human IL-16 Reference: GFH144-100 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
Recombinant Human IL-16 Reference: GFH144-1000 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
DNA ligase I blocking peptide Reference: GTX88393-PEP This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 214]
Recombinant Mouse IL-16 Reference: GFM49-2 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
MEST blocking peptide Reference: GTX88397-PEP This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 211]
Recombinant Mouse IL-16 Reference: GFM49-10 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
Recombinant Mouse IL-16 Reference: GFM49-100 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).
SEPT6 blocking peptide Reference: GTX88399-PEP This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 28]
Recombinant Mouse IL-16 Reference: GFM49-1000 Interleukin-16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin-2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).