RBM3 blocking peptide Reference: GTX47550-PEP This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 28]
Poly-L-Ornithine (0.1 mg/ml), 5 mg Reference: AP19 Poly-L-Ornithine is a synthetic amino acid chain that is positively charged having one hydrobromide per unit of ornithine. The molecular weight of Poly-L-Ornithine can vary significantly with lower molecular weight (30,000 Da) being less viscous and higher molecular weight (>300,000 Da) having more binding sites per molecule. This product’s molecular weight ranges from 70,000 to 150,000 Da yielding a solution viscosity for easy handling while providing sufficient binding sites for cell attachment.
THBS3 blocking peptide Reference: GTX47552-PEP The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 211]
Human Tropoelastin (lyophilized), 1 mg Reference: AP21 Human Tropoelastin is the precursor to the elastin molecule. It is not normally available in its native state since it becomes cross-linked immediately after its synthesis by the cell, during its export into the extracellular matrix. Tropoelastin is produced using recombinant production methods.
SLC47A1 blocking peptide Reference: GTX47554-PEP This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 28]
Recombinant Human ACRP-30 Reference: GFH156-5 The globular subunit of adipocyte complement-related protein of 30 kDa (globular ACRP-30) is a naturally occurring cleavage product of adiponectin. Produced exclusively by adipocytes, globular ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. Globular ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
Recombinant Human ACRP-30 Reference: GFH156-25 The globular subunit of adipocyte complement-related protein of 30 kDa (globular ACRP-30) is a naturally occurring cleavage product of adiponectin. Produced exclusively by adipocytes, globular ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. Globular ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
KCNJ1 / ROMK blocking peptide Reference: GTX47558-PEP Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 28]
Recombinant Human ACRP-30 Reference: GFH156-100 The globular subunit of adipocyte complement-related protein of 30 kDa (globular ACRP-30) is a naturally occurring cleavage product of adiponectin. Produced exclusively by adipocytes, globular ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. Globular ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
SULF2 blocking peptide Reference: GTX47559-PEP Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 25 [PubMed 16192265]).[supplied by OMIM, Mar 28]
Recombinant Human ACRP-30 Reference: GFH156-1000 The globular subunit of adipocyte complement-related protein of 30 kDa (globular ACRP-30) is a naturally occurring cleavage product of adiponectin. Produced exclusively by adipocytes, globular ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. Globular ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).