Lipoxygenase from Glycine max (soybean) - Purified Reference: 60700-5 Active, pure recombinant enzyme
DKK2 blocking peptide Reference: GTX41187-PEP This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 28]
iNOS (mouse, recombinant) Reference: 60864-250 Source: Active recombinant enzyme expressed in E. coli
ELKS blocking peptide Reference: GTX41192-PEP The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(1;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 28]
eNOS (bovine, recombinant) Reference: 60880-10 MW: 135 kDa • Source: recombinant enzyme; isolated from a Baculovirus overexpression system in Sf9 cells
UBE2I blocking peptide Reference: GTX41193-PEP The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 28]
PPARγ FL (human, recombinant from E. coli) Reference: 61700-25 Source: human recombinant N-terminal His-tagged protein expressed in E. coli · MW: ~60 kDa • PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARγ has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis, and cancer.
TL1A blocking peptide Reference: GTX41272-PEP The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 211]
PPARγ FL (human, recombinant from E. coli) Reference: 61700-50 Source: human recombinant N-terminal His-tagged protein expressed in E. coli · MW: ~60 kDa • PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARγ has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis, and cancer.
FABP4 (human recombinant) FITC conjugated Reference: 9001068-25 Source: recombinant N-terminal His-tagged protein expressed in E. coli • MW: 19 kDa