Category: Proteins & Peptides

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CRB1 blocking peptide

Reference: GTX32103-PEP

This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 212]

PVR/CD155 (mouse, recombinant)

Reference: 32073-100

Source: Active recombinant C-terminal human IgG1 Fc-His-tagged mouse PVR expressed in HEK293 cells • Amino acids: 28-345 • MW: 63 kDa

IL17 Receptor E blocking peptide

Reference: GTX32106-PEP

This gene encodes a protein that shares limited similarity with the interleukin-17 receptor. The function of the encoded protein has not yet been determined. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 21]

PVR/CD155 (mouse, recombinant)

Reference: 32073-50

Source: Active recombinant C-terminal human IgG1 Fc-His-tagged mouse PVR expressed in HEK293 cells • Amino acids: 28-345 • MW: 63 kDa

GILZ blocking peptide

Reference: GTX32107-PEP

The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 1, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 28]

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