CD86 Extracellular Domain (human, recombinant) Reference: 32010-100 Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD86 expressed in HEK293 cells • Amino acids: 20-239 • MW: 53.2 kDa
CADM3 blocking peptide Reference: GTX31935-PEP IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 67147) (Kakunaga et al., 25 [PubMed 15741237]).[supplied by OMIM, Mar 28]
CD86 Extracellular Domain (human, recombinant) Reference: 32010-200 Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD86 expressed in HEK293 cells • Amino acids: 20-239 • MW: 53.2 kDa
Nephrin blocking peptide Reference: GTX31936-PEP This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 29]
TIM-3 Extracellular Domain (human, recombinant) Reference: 32011-100 Source: Recombinant C-terminal mouse IgG2a Fc-tagged TIM-3 expressed in HEK293 cells • Amino acids: 22-200 • MW: 46.2 kDa
TIM-3 Extracellular Domain (human, recombinant) Reference: 32011-50 Source: Recombinant C-terminal mouse IgG2a Fc-tagged TIM-3 expressed in HEK293 cells • Amino acids: 22-200 • MW: 46.2 kDa
Galectin 9 Short Variant (human, recombinant) Reference: 32012-200 Source: Recombinant N-terminal human IgG1 Fc-tagged galectin 9 expressed in HEK293 cells • Amino acids: 2-323 • MW: 61.8 kDa
Cav3.2 blocking peptide Reference: GTX31939-PEP This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 28]
Galectin 9 Short Variant (human, recombinant) Reference: 32012-50 Source: Recombinant N-terminal human IgG1 Fc-tagged galectin 9 expressed in HEK293 cells • Amino acids: 2-323 • MW: 61.8 kDa
EPLIN blocking peptide Reference: GTX31940-PEP This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 211]