Category: Proteins & Peptides

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Importin 7 blocking peptide Importin 7 blocking peptide

Importin 7 blocking peptide

Reference: GTX15840-PEP
€0.00 (tax incl.)
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 2 potential...
MAD4 blocking peptide MAD4 blocking peptide

MAD4 blocking peptide

Reference: GTX15841-PEP
€0.00 (tax incl.)
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins...
RNF8 blocking peptide RNF8 blocking peptide

RNF8 blocking peptide

Reference: GTX15850-PEP
€0.00 (tax incl.)
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and...
GRAF blocking peptide GRAF blocking peptide

GRAF blocking peptide

Reference: GTX15916-PEP
€0.00 (tax incl.)
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these...
CPEB1 blocking peptide CPEB1 blocking peptide

CPEB1 blocking peptide

Reference: GTX15917-PEP
€0.00 (tax incl.)
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs....
CCNDBP1 blocking peptide CCNDBP1 blocking peptide

CCNDBP1 blocking peptide

Reference: GTX15960-PEP
€0.00 (tax incl.)
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin...
MLL2 blocking peptide MLL2 blocking peptide

MLL2 blocking peptide

Reference: GTX15962-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a...
ZIC5 blocking peptide ZIC5 blocking peptide

ZIC5 blocking peptide

Reference: GTX15965-PEP
€0.00 (tax incl.)
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type...
Cystatin B blocking peptide Cystatin B blocking peptide

Cystatin B blocking peptide

Reference: GTX15970-PEP
€0.00 (tax incl.)
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this...
MCL1 blocking peptide MCL1 blocking peptide

MCL1 blocking peptide

Reference: GTX16013-PEP
€0.00 (tax incl.)
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by...
DPAGT1 blocking peptide DPAGT1 blocking peptide

DPAGT1 blocking peptide

Reference: GTX16275-PEP
€0.00 (tax incl.)
The protein encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This...
MS4A6A blocking peptide MS4A6A blocking peptide

MS4A6A blocking peptide

Reference: GTX16310-PEP
€0.00 (tax incl.)
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique...
IL17 Receptor alpha blocking peptide IL17 Receptor alpha blocking peptide

IL17 Receptor alpha blocking peptide

Reference: GTX16598-PEP
€0.00 (tax incl.)
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by...
SnoN blocking peptide SnoN blocking peptide

SnoN blocking peptide

Reference: GTX16977-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds...
DEDD2 blocking peptide DEDD2 blocking peptide

DEDD2 blocking peptide

Reference: GTX16979-PEP
€0.00 (tax incl.)
This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced...
BIRC6 blocking peptide BIRC6 blocking peptide

BIRC6 blocking peptide

Reference: GTX16980-PEP
€0.00 (tax incl.)
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the...
Bok blocking peptide Bok blocking peptide

Bok blocking peptide

Reference: GTX16981-PEP
€0.00 (tax incl.)
The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies...
AES blocking peptide AES blocking peptide

AES blocking peptide

Reference: GTX16982-PEP
€0.00 (tax incl.)
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which...
AES blocking peptide AES blocking peptide

AES blocking peptide

Reference: GTX16983-PEP
€0.00 (tax incl.)
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which...
ATG7 blocking peptide ATG7 blocking peptide

ATG7 blocking peptide

Reference: GTX16984-PEP
€0.00 (tax incl.)
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein...
ATG7 blocking peptide ATG7 blocking peptide

ATG7 blocking peptide

Reference: GTX16985-PEP
€0.00 (tax incl.)
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein...
BANF1 blocking peptide BANF1 blocking peptide

BANF1 blocking peptide

Reference: GTX16986-PEP
€0.00 (tax incl.)
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein...
BANF1 blocking peptide BANF1 blocking peptide

BANF1 blocking peptide

Reference: GTX16987-PEP
€0.00 (tax incl.)
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein...
DARC blocking peptide DARC blocking peptide

DARC blocking peptide

Reference: GTX16988-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and...
DARC blocking peptide DARC blocking peptide

DARC blocking peptide

Reference: GTX16989-PEP
€0.00 (tax incl.)
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and...
EMX2 blocking peptide EMX2 blocking peptide

EMX2 blocking peptide

Reference: GTX16990-PEP
€0.00 (tax incl.)
This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal...
MICA blocking peptide MICA blocking peptide

MICA blocking peptide

Reference: GTX16991-PEP
€0.00 (tax incl.)
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with...
FEZ1 blocking peptide FEZ1 blocking peptide

FEZ1 blocking peptide

Reference: GTX16992-PEP
€0.00 (tax incl.)
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants...
LIS1 blocking peptide LIS1 blocking peptide

LIS1 blocking peptide

Reference: GTX16993-PEP
€0.00 (tax incl.)
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the...
SLITRK2 blocking peptide SLITRK2 blocking peptide

SLITRK2 blocking peptide

Reference: GTX16999-PEP
€0.00 (tax incl.)
This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in...
SLITRK2 blocking peptide SLITRK2 blocking peptide

SLITRK2 blocking peptide

Reference: GTX17000-PEP
€0.00 (tax incl.)
This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in...
Wnt10b blocking peptide Wnt10b blocking peptide

Wnt10b blocking peptide

Reference: GTX17006-PEP
€0.00 (tax incl.)
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of...
BRF2 blocking peptide BRF2 blocking peptide

BRF2 blocking peptide

Reference: GTX17011-PEP
€0.00 (tax incl.)
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this...
ERp57 blocking peptide ERp57 blocking peptide

ERp57 blocking peptide

Reference: GTX17012-PEP
€0.00 (tax incl.)
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a...
ALDH3A2 blocking peptide ALDH3A2 blocking peptide

ALDH3A2 blocking peptide

Reference: GTX17013-PEP
€0.00 (tax incl.)
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain...
ALDH5A1 blocking peptide ALDH5A1 blocking peptide

ALDH5A1 blocking peptide

Reference: GTX17016-PEP
€0.00 (tax incl.)
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as...
HINT1 blocking peptide HINT1 blocking peptide

HINT1 blocking peptide

Reference: GTX17017-PEP
€0.00 (tax incl.)
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates...
FBXL2 blocking peptide FBXL2 blocking peptide

FBXL2 blocking peptide

Reference: GTX17018-PEP
€0.00 (tax incl.)
This gene encodes a member of the F-box protein family which is characterized by an approximately 4 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase...
MAML1 blocking peptide MAML1 blocking peptide

MAML1 blocking peptide

Reference: GTX17019-PEP
€0.00 (tax incl.)
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a...
AAK1 blocking peptide AAK1 blocking peptide

AAK1 blocking peptide

Reference: GTX17021-PEP
€0.00 (tax incl.)
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This...
PDLIM1 blocking peptide PDLIM1 blocking peptide

PDLIM1 blocking peptide

Reference: GTX17022-PEP
€0.00 (tax incl.)
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a...
AAK1 blocking peptide AAK1 blocking peptide

AAK1 blocking peptide

Reference: GTX17023-PEP
€0.00 (tax incl.)
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This...
AIPL1 blocking peptide AIPL1 blocking peptide

AIPL1 blocking peptide

Reference: GTX17024-PEP
€0.00 (tax incl.)
Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at...
FOXO3A blocking peptide FOXO3A blocking peptide

FOXO3A blocking peptide

Reference: GTX17026-PEP
€0.00 (tax incl.)
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for...
AIPL1 blocking peptide AIPL1 blocking peptide

AIPL1 blocking peptide

Reference: GTX17027-PEP
€0.00 (tax incl.)
Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at...
SLP76 blocking peptide SLP76 blocking peptide

SLP76 blocking peptide

Reference: GTX17029-PEP
€0.00 (tax incl.)
SLP-76 was originally identified as a substrate of the ZAP-7 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome...
EBI3 blocking peptide EBI3 blocking peptide

EBI3 blocking peptide

Reference: GTX17030-PEP
€0.00 (tax incl.)
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with...
Bim blocking peptide Bim blocking peptide

Bim blocking peptide

Reference: GTX17031-PEP
€0.00 (tax incl.)
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...
LAT blocking peptide LAT blocking peptide

LAT blocking peptide

Reference: GTX17032-PEP
€0.00 (tax incl.)
The protein encoded by this gene is phosphorylated by ZAP-7/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to...
RAN blocking peptide RAN blocking peptide

RAN blocking peptide

Reference: GTX17033-PEP
€0.00 (tax incl.)
RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also...
RanBP1 blocking peptide RanBP1 blocking peptide

RanBP1 blocking peptide

Reference: GTX17034-PEP
€0.00 (tax incl.)
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does...
FOXP4 blocking peptide FOXP4 blocking peptide

FOXP4 blocking peptide

Reference: GTX17035-PEP
€0.00 (tax incl.)
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription...
EBI3 blocking peptide EBI3 blocking peptide

EBI3 blocking peptide

Reference: GTX17036-PEP
€0.00 (tax incl.)
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with...
GALNT10 blocking peptide GALNT10 blocking peptide

GALNT10 blocking peptide

Reference: GTX17042-PEP
€0.00 (tax incl.)
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from...
GALNT10 blocking peptide GALNT10 blocking peptide

GALNT10 blocking peptide

Reference: GTX17043-PEP
€0.00 (tax incl.)
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from...
CENPO blocking peptide CENPO blocking peptide

CENPO blocking peptide

Reference: GTX17045-PEP
€0.00 (tax incl.)
This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and...
PLEKHM1 blocking peptide PLEKHM1 blocking peptide

PLEKHM1 blocking peptide

Reference: GTX17056-PEP
€0.00 (tax incl.)
The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis...
Synaptogyrin 2 blocking peptide Synaptogyrin 2 blocking peptide

Synaptogyrin 2 blocking peptide

Reference: GTX17057-PEP
€0.00 (tax incl.)
This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a...
CDC27 blocking peptide CDC27 blocking peptide

CDC27 blocking peptide

Reference: GTX17058-PEP
€0.00 (tax incl.)
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting...
APC5 blocking peptide APC5 blocking peptide

APC5 blocking peptide

Reference: GTX17060-PEP
€0.00 (tax incl.)
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell...
Apc6 blocking peptide Apc6 blocking peptide

Apc6 blocking peptide

Reference: GTX17065-PEP
€0.00 (tax incl.)
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis....
CDC23 blocking peptide CDC23 blocking peptide

CDC23 blocking peptide

Reference: GTX17066-PEP
€0.00 (tax incl.)
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of...
Apc10 blocking peptide Apc10 blocking peptide

Apc10 blocking peptide

Reference: GTX17067-PEP
€0.00 (tax incl.)
ANAPC1 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by...
SIRT4 blocking peptide SIRT4 blocking peptide

SIRT4 blocking peptide

Reference: GTX17074-PEP
€0.00 (tax incl.)
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions...
SIRT6 blocking peptide SIRT6 blocking peptide

SIRT6 blocking peptide

Reference: GTX17089-PEP
€0.00 (tax incl.)
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions...
IDH2 blocking peptide IDH2 blocking peptide

IDH2 blocking peptide

Reference: GTX17090-PEP
€0.00 (tax incl.)
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other...
BANP blocking peptide BANP blocking peptide

BANP blocking peptide

Reference: GTX17092-PEP
€0.00 (tax incl.)
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator....
Klotho blocking peptide Klotho blocking peptide

Klotho blocking peptide

Reference: GTX17093-PEP
€0.00 (tax incl.)
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors...
ZMYM3 blocking peptide ZMYM3 blocking peptide

ZMYM3 blocking peptide

Reference: GTX17097-PEP
€0.00 (tax incl.)
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone...
Nkx3.2 blocking peptide Nkx3.2 blocking peptide

Nkx3.2 blocking peptide

Reference: GTX17098-PEP
€0.00 (tax incl.)
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development. [provided by RefSeq, Jul 28]

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