ECT2 BRCT domains (human, recombinant) Reference: 14168-1 Source: Recombinant N-terminal GST-tagged protein expressed in E. coli • MW: 50.2 kDa
FYB blocking peptide Reference: GTX31762-PEP The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 211]
LIG4 BRCT domains (human, recombinant) Reference: 14169-100 Source: Recombinant N-terminal GST-tagged protein expressed in E. coli • Mr: 57.6 kDa
TP53BP1 BRCT domains (human recombinant) Reference: 14171-100 Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)
TP53BP1 BRCT domains (human recombinant) Reference: 14171-25 Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)
BRCC36 blocking peptide Reference: GTX31765-PEP This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 211]
TP53BP1 BRCT domains (human recombinant) Reference: 14171-50 Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)
GSTP1 blocking peptide Reference: GTX31766-PEP Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 28]
FEN1 (human, recombinant) Reference: 14199-100 Active • Host: E. coli • AA: 2-380 (full length) • Tag: C-terminal His • MW: 43.8 kDa