Adiponectin, human recombinant protein Reference: P1113-.025 Adiponectin, expressed in E. coli, suitable for cell culture.
FOXP3 blocking peptide Reference: GTX31517-PEP The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 28]
Adiponectin, human recombinant protein Reference: P1113-.1 Adiponectin, expressed in E. coli, suitable for cell culture.
Adiponectin, human recombinant protein Reference: P1113-1 Adiponectin, expressed in E. coli, suitable for cell culture.
GRIP1 blocking peptide Reference: GTX31521-PEP This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 21]
Adiponectin, murine recombinant protein Reference: P1114-.025 Adiponectin, expressed in E. coli, suitable for cell culture.
IL15 Receptor alpha blocking peptide Reference: GTX31523-PEP This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 21]
Adiponectin, murine recombinant protein Reference: P1114-.1 Adiponectin, expressed in E. coli, suitable for cell culture.
CD59 blocking peptide Reference: GTX31524-PEP This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 28]
Adiponectin, murine recombinant protein Reference: P1114-1 Adiponectin, expressed in E. coli, suitable for cell culture.
RC3H1 blocking peptide Reference: GTX31528-PEP RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al., 25 [PubMed 15917799]). The roquin protein is distinguished by the presence of a CCCH zinc finger found in RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and stability.[supplied by OMIM, Mar 28]