Recombinant Human Fibrinogen gamma chain(FGG) Reference: CSB-EP008651HU_100 Together with fibrinogen alpha and fibrinogen beta, polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Recombinant Human Fibrinogen gamma chain(FGG) Reference: CSB-EP008651HU_20 Together with fibrinogen alpha and fibrinogen beta, polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Recombinant Human Acidic fibroblast growth factor intracellular-binding... Reference: CSB-EP008671HU_1 May be involved in mitogenic function of FGF1.
Recombinant Human Acidic fibroblast growth factor intracellular-binding... Reference: CSB-EP008671HU_100 May be involved in mitogenic function of FGF1.
Recombinant Human Acidic fibroblast growth factor intracellular-binding... Reference: CSB-EP008671HU_20 May be involved in mitogenic function of FGF1.
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1A(FKBP1A),partial Reference: CSB-EP008691HU1_1 Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1A(FKBP1A),partial Reference: CSB-EP008691HU1_100 Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP1A(FKBP1A),partial Reference: CSB-EP008691HU1_20 Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP3(FKBP3) Reference: CSB-EP008699HU_1 FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct Cytoplasmic domain signal transmission pathways. PPIases accelerate the folding of proteins.