IL-7, murine recombinant Reference: P1025-.05 IL-7, lymphoid cell growth factor, expressed in E.Coli, cross-species reactive.
IL-7, murine recombinant Reference: P1025-1 IL-7, lymphoid cell growth factor, expressed in E.Coli, cross-species reactive.
SCF blocking peptide Reference: GTX31379-PEP This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 28]
IL-8 (77 a.a.), human recombinant Reference: P1026-.025 IL-8, neutrophil chemokine, expressed in E.Coli.
GPR3 blocking peptide Reference: GTX31380-PEP This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 212]
IL-8 (77 a.a.), human recombinant Reference: P1026-1 IL-8, neutrophil chemokine, expressed in E.Coli.
CD81 blocking peptide Reference: GTX31381-PEP The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 214]
IL-10, human recombinant protein Reference: P1028-.01 IL-10, immunosuppressive cytokine, expressed in E.Coli, active on murine cells.
MC4 Receptor blocking peptide Reference: GTX31382-PEP The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 21]
IL-10, human recombinant protein Reference: P1028-.05 IL-10, immunosuppressive cytokine, expressed in E.Coli, active on murine cells.
THEM4 blocking peptide Reference: GTX31383-PEP Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 28]