Recombinant Human Arachidonate 12-lipoxygenase, 12S-type(ALOX12) Reference: CSB-EP001617HU_1 Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to-hydroperoxyeicosatetraenoic acid/-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Recombinant Human Arachidonate 12-lipoxygenase, 12S-type(ALOX12) Reference: CSB-EP001617HU_100 Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to-hydroperoxyeicosatetraenoic acid/-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Recombinant Human Arachidonate 12-lipoxygenase, 12S-type(ALOX12) Reference: CSB-EP001617HU_20 Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to-hydroperoxyeicosatetraenoic acid/-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Recombinant Human Intestinal-type alkaline phosphatase(ALPI) Reference: CSB-EP001627HU_1 Miscellaneous. In most mammals there are four different isozymes: placental, germ cell, intestinal and tissue non-specific (liver/bone/kidney). Catalytic activity a phosphate monoester + H2O = an alcohol + phosphate
Recombinant Human Intestinal-type alkaline phosphatase(ALPI) Reference: CSB-EP001627HU_100 Miscellaneous. In most mammals there are four different isozymes: placental, germ cell, intestinal and tissue non-specific (liver/bone/kidney). Catalytic activity a phosphate monoester + H2O = an alcohol + phosphate