Angiopoietin 1 peptide Reference: GTX29076 This peptide can be used as a blocking peptide for the rabbit polyclonal to Ang-1 (GTX28451).
Angiopoietin 2 peptide Reference: GTX29077 Intended for use as a control peptide when used with anti-Mouse Angiopoietin 2 (GTX28452) to block specific interaction of anti-Mouse Angiopoietin 2 with Mouse Angiopoietin 2.
Osteopontin peptide Reference: GTX29078 This peptide can be used as a blocking peptide for the rabbit polyclonal to Osteopontin (GT28448).
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] Reference: A1085-1 Transcriptional repressor
SHP2 blocking peptide Reference: GTX29214-PEP The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 212]
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] Reference: A1085-5 Transcriptional repressor
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] Reference: A1085-10 Transcriptional repressor
PUMA peptide Reference: GTX29644 Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b (1). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.