MIG (CXCL9), mouse, Reference: D-65811 Recombinant Mouse Monokine Induced by Interferon-gamma (CXCL9)
RGS1 blocking peptide Reference: GTX22715-PEP This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 12 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 28]
MIP-1 beta (CCL4), mouse, Reference: D-65822 Recombinant Mouse Macrophage Inflammatory Protein 1-beta (CCL4)
KLF8 blocking peptide Reference: GTX22747-PEP This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 29]
MIP-1 alpha (CCL3), mouse, Reference: D-65833 Recombinant Mouse Macrophage Inflammatory Protein 1-alpha (CCL3)
GULP1 blocking peptide Reference: GTX22751-PEP The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 211]
MIP-1 gamma (CCL9/10), recombinant Reference: D-65844 Recombinant Mouse Macrophage Inflammatory Protein 1-gamma
HLTF blocking peptide Reference: GTX22835-PEP This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 28]
MIP-3 alpha (CCL20), mouse, recombinant Reference: D-65866 Recombinant Mouse Macrophage Inflammatory Protein 3-alpha (CCL20)
Hec1 blocking peptide Reference: GTX23393-PEP This gene encodes a component of the NDC8 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 211]