TNF-alpha, mouse, recombinant Reference: D-63720 Recombinant Mouse Tumor Necrosis Factor alpha (E. coli-derived)
Musculin blocking peptide Reference: GTX21330-PEP The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 28]
APRIL, mouse, recombinant Reference: D-63745 Recombinant Mouse APRIL (A Proliferation Inducing Ligand; TALL-2, TRDL-1a, TNFSF13)
OPG (OCIF), mouse, recombinant (Sf9) Reference: D-63750 Recombinant Mouse Osteoprotegerin (Osteoclastogenesis Inhibitory Factor; Sf9 cell-derived)
PPP2R5B blocking peptide Reference: GTX21366-PEP The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 28]
Cortactin/EMS1 blocking peptide Reference: GTX21374-PEP This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 21]
MCP-1 (JE, CCL2), mouse, Reference: D-64030 Recombinant Mouse JE (Monocyte Chemotactic Protein, CCL2)
DDAH2 blocking peptide Reference: GTX21383-PEP This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 28]
Notch1 intra peptide Reference: GTX21390 This peptide can be used as a blocking peptide for the rabbit polyclonal to Notch 1 (intra)- GTX28387.