IFN-lambda-2 (IL-28A), mouse, recombinant Reference: D-60732 Recombinant Mouse Interferon lambda-2 (IL-28A)
MIP1 beta blocking peptide Reference: GTX17201-PEP The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 212]
HE4 blocking peptide Reference: GTX17207-PEP This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 28]
ERAP2 blocking peptide Reference: GTX17208-PEP Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 66832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 1947) (Tanioka et al., 23 [PubMed 12799365]).[supplied by OMIM, Mar 28]
IGF-BP6, mouse, recombinant (Sf9) Reference: D-60855 Recombinant Mouse Insulin Like Growth Factor Binding Protein 6 (Sf9 cell-derived)
CD160 blocking peptide Reference: GTX17209-PEP CD16 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD16 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD16 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD16 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD16 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD16 is expressed on all intestinal intraepithelial lymphocytes. CD16 shows a broad specificity for binding to both classical and nonclassical MH