Human DYNLRB1 protein, His tag Reference: GTX68785-pro This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 213]
Human ATG10 protein, His tag Reference: GTX68788-pro Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG1 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 6968)-ATG5 (MIM 64261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 61242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 23 [PubMed 1289687]).[supplied by OMIM, Mar 28]
Human RBP5 protein, His tag Reference: GTX68789-pro The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 216]
Rat nm23-H2 protein, His tag Reference: GTX68790-pro kinase involved in synthesis of nucleoside triphosphates [RGD, Feb 26]