Category: Proteins & Peptides

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Reference: C-68564

Recombinant Human Tissue Inhibitor of Metalloproteinases 2 (HEK cell-derived)

Reference: GTX17092-PEP

This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 21]

Reference: GTX17093-PEP

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 28]

Reference: C-69111

Recombinant Human Triggering Receptor Expressed on Monocytes 1, (CD354; E. coli-derived)

Reference: C-69112

Recombinant Human Triggering Receptor Expressed on Monocytes 2 (E. coli-derived)

Reference: GTX17097-PEP

This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 21]