PtdIns-(3,4,5)-P3 Binding Protein

Source: recombinant N-terminal GST-tagged protein purified from E. coli · Mr: ~41.7 kDa (15.4 kDa native; 26.3 kDa GST-tagged) • PtdIns-(3,4,5)-P3 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(3,4,5)-P3. PtdIns phosphates play a critical role in the generation and transmission of cellular signals. Due to PtdIns-(3,4,5)-P3 binding protein’s unique affinity for PtdIns-(3,4,5)-P3, this protein can be used to detect product formed by PI3-kinase in in vitro assays.