Human PROSC protein, His tag

This gene encodes a pyridoxal 5-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 217]