CARD10 blocking peptide

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD1 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 16411) through BCL1 (MIM 63517) (Wang et al., 21 [PubMed 11259443]).[supplied by OMIM, Mar 28]