c-Rel peptide

c-Rel is the cellular cognate of v-Rel, the avian reticuloendo-theliosis virus strain T transforming gene. V-Rel encodes a 59kDa phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein which is cytoplasmic. C-Rel was shown to represent a constituent of the kB site binding transcription factor NFkB, which plays a crucial role in the expression of immunoglobulin k light chain gene.