Oxidized LDL Uptake Assay Kit

The oxidation of low density lipoprotein is thought to be one of the first steps in atherosclerosis. The uptake of oxidized LDL (oxLDL) by macrophages activates pro-inflammatory mediators that promote disease progression. Cayman’s Oxidized LDL Uptake Assay Kit is a convenient tool to study modulators of cellular uptake of oxLDL. The kit employs a fluorescently tagged, human oxLDL along with myricetin, an inhibitor of uptake that reduces CD36 expression. The reagents provided in this kit are sufficient to run a single plate of cultured cells by either FC or FM.