Seribantumab

Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models.
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Reference:
HY-P99268
Product Details
HY-P99268

Data sheet

Size
Multiple sizes
Reactivity
EGFR; Apoptosis
Application
Cancer-Kinase/protease
CAS
1334296-12-6

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