Organelle Marker Antibody Panel

Poly(ADP-ribosyl)transferase (PARP1) is a chromatin-associated enzyme, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. This antibody is a control for nuclear localization. PARP1 has a molecular weight of 113 kDa. Alpha-tubulin is one of the two the major structural components of microtubules, part of the eukaryotic cytoskeleton. The alpha-tubulin 4a subunit is a highly conserved among species. This antibody is a control for cytoplasmic localization. Alpha-tubulin has a molecular weight of 5 kDa. Calnexin is a calcium-binding molecular chaperone protein that plays a critical role in N-glycosylation of proteins. Calnexin is localized to the endoplasmic reticulum (ER) and has a predicted molecular weight of 66 kDa. Aldo-keto reductase family 7 (AKR7) is an enzyme involved in the detoxification of aldehydes and ketones. It is localized to the golgi apparatus and has a predicted molecular weight of 4 kDa. NHP2-like protein 1 is a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It is localized to the nucleolus and has a predicted molecular weight of 14 kDa