Primary antibodies (638)

anti-TIGIT (human), mAb (ANCTG6/10A6) (R-PE)

Reference: ANC-340-050

€0.00 (tax incl.)

TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a novel member of the immunoglobulin super family (IgSF). TIGIT and CD226 bind the same ligands, the two nectin-family members poliovirus receptor (PVR) and...

anti-polyHistidine, mAb (ANC3G4-9)

Reference: ANC-801-020

€0.00 (tax incl.)

A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein. Polyhistidine-tags are often used for affinity...

anti-polyHistidine, mAb (ANC3G4-9) (HRP)

Reference: ANC-801-990

€0.00 (tax incl.)

A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein. Polyhistidine-tags are often used for affinity...

anti-MSH2 (C-Term) (human), Rabbit Monoclonal (RM478)

Reference: REV-31-1370-00

€0.00 (tax incl.)

The mismatch repair (MMR) proteins are required to maintain genomic integrity in prokaryotes and eukaryotes, by correcting single mismatches and short unpaired regions, such as small insertions and deletions. In...

anti-p42 MAPK (Erk2), Rabbit Monoclonal (RM483)

Reference: REV-31-1375-00

€0.00 (tax incl.)

Extracellular signal-regulated kinases 1 and 2 (also known as ERK1/2, p44/42, or MAPK3/1) belong to a family of conserved serine/threonine protein kinases known as mitogen-activated protein kinases (MAPKs) that are...

anti-Phospho-Myl2 (Myosin Light Chain 2v) (Ser19), Rabbit Monoclonal (RM484)

Reference: REV-31-1376-00

€0.00 (tax incl.)

Myosin is composed of six polypeptide chains: two identical heavy chains and two pairs of light chains. Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC or RLC, LC20), has many isoforms...

anti-DDIT3 (human), Rabbit Monoclonal (RM485)

Reference: REV-31-1377-00

€0.00 (tax incl.)

DDIT3 [GADD153] is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical...

anti-CAIX (CA9), Rabbit Monoclonal (RM486)

Reference: REV-31-1378-00

€0.00 (tax incl.)

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that...

anti-Phospho-Smad1 (Ser463/465) / Smad5 (Ser463/465) / Smad9 (Ser465/467), Rabbit Monoclonal (RM487)

Reference: REV-31-1379-00

€0.00 (tax incl.)

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmits TGF-beta signals from the cell surface into the nucleus. Three distinct classes of Smads...

anti-Phospho-ULK1 (Ser757), Rabbit Monoclonal (RM488)

Reference: REV-31-1380-00

€0.00 (tax incl.)

ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is...

anti-MUC-1 (Mucin-1) (human), Rabbit Monoclonal (RM489)

Reference: REV-31-1381-00

€0.00 (tax incl.)

MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. MUC1 is a transmembrane glycoprotein with a large mucin-like extracellular...

anti-TIA1 (human), Rabbit Monoclonal (RM490)

Reference: REV-31-1382-00

€0.00 (tax incl.)

TIA1, also named as p40-TIA-1, is involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). It possesses...

anti-Sortilin (human), mAb (rec.) (blocking) (preservative free) [Latozinemab]

Reference: AG-27B-7000PF

€0.00 (tax incl.)

Sortilin is a type I transmembrane multiligand receptor that is a member of the Vacuolar protein sorting 10 protein (Vps10p) domain receptor family. It is a 95 kDa protein, ubiquitously expressed, although most...

anti-APRIL, mAb (Heaty-1)

Reference: AG-20B-0082

€0.00 (tax incl.)

APRIL is a secreted cytokine, belonging to the TNF superfamily that binds to transmembrane activator and CAML interactor (TACI), B cell maturation antigen (BCMA) and can interact with carbohydrate side chains of...

anti-Periostin, mAb (blocking) (OC-20) (preservative free)

Reference: AG-20B-6000YPF

€0.00 (tax incl.)

Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are...

anti-Fibronectin (EDA), mAb (blocking) (IST-9) (preservative free)

Reference: AG-20B-6001YPF

€0.00 (tax incl.)

Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and...

anti-Isthmin-1, mAb (rec.) (Giusepi-1-4)

Reference: AG-27B-0022

€0.00 (tax incl.)

Isthmin-1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain hind brain organizer called isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein...

anti-5-Carboxylcytosine (5-caC), Rabbit Monoclonal (RM462)

Reference: REV-31-1354-00

€0.00 (tax incl.)

5-Carboxylcytosine (5-caC) is a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has...

anti-cAMP, Rabbit Monoclonal (RM466)

Reference: REV-31-1358-00

€0.00 (tax incl.)

Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger...

anti-cGMP, Rabbit Monoclonal (RM467)

Reference: REV-31-1359-00

€0.00 (tax incl.)

Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with...

anti-INI1 (SNF5/SMARCB1), Rabbit Monoclonal (RM468)

Reference: REV-31-1360-00

€0.00 (tax incl.)

INI1 (also known as SNF5 or SMARCB1) is a protein that is involved in the regulation of transcription, replication, and repair of DNA. It is a subunit of the SWI/SNF chromatin remodeling complex, which helps to open...

anti-MerTK (mouse), Rabbit Monoclonal (RM469)

Reference: REV-31-1361-00

€0.00 (tax incl.)

MerTK is a transmembrane receptor tyrosine kinase (RTK) that is mainly expressed in dendritic cells (DCs) and macrophages. It is a member of the TYRO3/AXL/MER (TAM) receptor kinase family, which also includes TYRO3...

anti-p44 MAPK (Erk1), Rabbit Monoclonal (RM470)

Reference: REV-31-1362-00

€0.00 (tax incl.)

Extracellular signal-regulated kinases 1 and 2 (also known as ERK1/2, p44/42, or MAPK3/1) belong to a family of conserved serine/threonine protein kinases known as mitogen-activated protein kinases (MAPKs) that are...

anti-CD137 (4-1BB), Rabbit Monoclonal (RM471)

Reference: REV-31-1363-00

€0.00 (tax incl.)

CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137...

anti-FAK (Focal adhesion kinase 1), Rabbit Monoclonal (RM472)

Reference: REV-31-1364-00

€0.00 (tax incl.)

FAK1 (Focal Adhesion Kinase 1) is a non-receptor protein tyrosine kinase that is involved in the regulation of cell adhesion, migration, and survival. It is a member of the Src family of kinases. FAK1 is activated by...

anti-Stat6, Rabbit Monoclonal (RM473)

Reference: REV-31-1365-00

€0.00 (tax incl.)

STAT6 (Signal transducer and activator of transcription 6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit...

anti-5-Formylcytosines (5-fC), Rabbit Monoclonal (RM477)

Reference: REV-31-1369-00

€0.00 (tax incl.)

5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase...

anti-Trimethyl-Histone H3 (Lys36), Rabbit Monoclonal (RM491)

Reference: REV-31-1383-00

€0.00 (tax incl.)

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role...

anti-alpha-synuclein (SYUA), Rabbit Monoclonal (RM492)

Reference: REV-31-1384-00

€0.00 (tax incl.)

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane...

anti-His-Tag, Rabbit Monoclonal (RM146X)

Reference: REV-38-1048-00

€0.00 (tax incl.)

His-tag is a series of six to nine histidine residues fused to either the carboxyl or amino terminus of a recombinant protein. The small size of the His-tag, compared with other common epitope tags, makes it less...

anti-EGFR (human), Rabbit Monoclonal (RM493)

Reference: REV-31-1385-00

€0.00 (tax incl.)

EGFR (Epidermal growth factor receptor, HER1, ErbB1) belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of...

anti-ER-alpha (human), Rabbit Monoclonal (RM494)

Reference: REV-31-1386-00

€0.00 (tax incl.)

Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone,...

anti-CDX2 (human), Rabbit Monoclonal (RM495)

Reference: REV-31-1387-00

€0.00 (tax incl.)

CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of...

anti-CD68 (human), Rabbit Monoclonal (RM496)

Reference: REV-31-1388-00

€0.00 (tax incl.)

CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and...

anti-CD45 (human), Rabbit Monoclonal (RM497)

Reference: REV-31-1389-00

€0.00 (tax incl.)

CD45 (LCA; Leukocyte Common Antigen; Protein tyrosine phosphatase, receptor type, C; PTPRC) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells. CD45 is...

anti-LAIR1 (human), Rabbit Monoclonal (RM498)

Reference: REV-31-1390-00

€0.00 (tax incl.)

LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on the cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in...

anti-Galectin-9 (human), Rabbit Monoclonal (RM499)

Reference: REV-31-1391-00

€0.00 (tax incl.)

Galectin-9 (Gal-9), a beta-galactoside-binding protein, primarily plays an immunosuppressive role in the tumor microenvironment, via binding with several cell surface receptors expressed on immune cells. Although...

anti-Phospho-DNA-PKcs (Ser2056) (human), Rabbit Monoclonal (RM500)

Reference: REV-31-1392-00

€0.00 (tax incl.)

DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ)....

anti-CD27 (human), Rabbit Monoclonal (RM501)

Reference: REV-31-1393-00

€0.00 (tax incl.)

CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell...

anti-VISTA, Rabbit Monoclonal (RM503)

Reference: REV-31-1395-00

€0.00 (tax incl.)

Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with...

anti-GCDFP-15 (human), Rabbit Monoclonal (RM504)

Reference: REV-31-1396-00

€0.00 (tax incl.)

Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is...

anti-DNA-PKcs (human), Rabbit Monoclonal (RM505)

Reference: REV-31-1397-00

€0.00 (tax incl.)

DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ)....

anti-MerTK (human), Rabbit Monoclonal (RM506)

Reference: REV-31-1398-00

€0.00 (tax incl.)

MerTK is a transmembrane receptor tyrosine kinase (RTK) that is mainly expressed in dendritic cells (DCs) and macrophages. It is a member of the TYRO3/AXL/MER (TAM) receptor kinase family, which also includes TYRO3...

anti-UP2 (Uroplakin-2) (human), Rabbit Monoclonal (RM507)

Reference: REV-31-1399-00

€0.00 (tax incl.)

The protein components of uroplaques are composed of uroplakins (UPs), which are a family of transmembrane proteins, including UPIa (27 kDa), UPIb (28 kDa), UPII (15 kDa), and UPIIIa (47 kDa). UPs are exclusively...

anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-1) (Fc LAEA-PG)

Reference: AG-27B-0023

€0.00 (tax incl.)

APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes....

anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-1) (Fc LAEA-PG) (preservative free)

Reference: AG-27B-0023PF

€0.00 (tax incl.)

APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes....

anti-CD8 (human), mAb (14) (APC)

Reference: ANC-154-060

€0.00 (tax incl.)

Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kDa. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-receptor involved in...

anti-CD44 (human), mAb (BU52) (Fab)

Reference: ANC-193-580

€0.00 (tax incl.)

Human CD44 molecules appear to serve as lymphocyte adhesion molecules with numerous functions in extracellular matrix binding, cell migration, hemopoisis and lymphocyte homing.

anti-CD74 (human), mAb (M-B741) (APC)

Reference: ANC-226-060

€0.00 (tax incl.)

Human CD74 is expressed intracellularly and on the cell surface of MHC Class II positive cells such as B cells, monocytes, macrophages, Langerhans cells and dendritic cells. CD74 has several important functions...

Human IgG1 Isotype Control (APC)

Reference: ANC-295-060

€0.00 (tax incl.)

Human IgG1kappa from human myeloma plasma is used as a negative control for work involving human IgG1 isotype antibodies or recombinant proteins.

anti-CD40 (human), mAb (EA-5) (APC)

Reference: ANC-300-060

€0.00 (tax incl.)

CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and...

anti-Perforin (human), mAb (deltaG9) (APC)

Reference: ANC-358-060

€0.00 (tax incl.)

Human perforin (cytolysin) is believed to be one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Perforin expression is constitutive on NK cells, but increases in...

anti-CD152 [CTLA-4] (human), mAb (ANC152.2/8H5) (APC)

Reference: ANC-359-060

€0.00 (tax incl.)

Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function...

anti-CD137 (human), mAb (4B4-1) (Fab)

Reference: ANC-360-580

€0.00 (tax incl.)

Human CD137 (4-1BB) is expressed on activated T cells within 24-48 hours of activation. CD137 is a type I membrane protein and a member of the TNF receptor superfamily. CD137 appears to be important for T cell...

anti-GATA3, Rabbit Monoclonal (RM482)

Reference: REV-31-1374-00

€0.00 (tax incl.)

GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production...

anti-FGL1 (human), Rabbit Monoclonal (RM502)

Reference: REV-31-1394-00

€0.00 (tax incl.)

FGL1 (Fibrinogen-like protein 1, also called Hepatocyte-derived fibrinogen-related protein 1, HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript...

anti-CLDN 18.2, Rabbit Monoclonal (RM510)

Reference: REV-31-1402-00

€0.00 (tax incl.)

Claudins (CLDNs) are a family of proteins that form tight junctions and maintain the polarity of epithelial and endothelial cells. CLDN18 is specifically expressed in the stomach and lungs. Of the two CLDN18 isoform...

anti-PTEN (human), Rabbit Monoclonal (RM511)

Reference: REV-31-1403-00

€0.00 (tax incl.)

PTEN (phosphatase and tensin homologue deleted on chromosome ten) is a tumor suppressor implicated in a wide variety of human cancers. PTEN encodes a 403 amino acid polypeptide and contains a tensin like domain as...

anti-IgA (human), Rabbit Monoclonal (RM513)

Reference: REV-31-1405-00

€0.00 (tax incl.)

Immunoglobulin A (IgA) is an antibody isotype that plays a crucial role in the immune function of mucous membranes. IgA has two subclasses (IgA1 and IgA2) and can be produced as a monomeric as well as a dimeric form....

anti-CD155 [PVR] (human), Rabbit Monoclonal (RM514)

Reference: REV-31-1406-00

€0.00 (tax incl.)

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96...

anti-VEGFR2 (human), Rabbit Monoclonal (RM515)

Reference: REV-31-1407-00

€0.00 (tax incl.)

Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been...

anti-WT1 (human), Rabbit Monoclonal (RM516)

Reference: REV-31-1408-00

€0.00 (tax incl.)

WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the...

anti-MUC-17 (Mucin-17) (human), Rabbit Monoclonal (RM517)

Reference: REV-31-1409-00

€0.00 (tax incl.)

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC-17, contains an extended, repetitive...

anti-TRPS1, Rabbit Monoclonal (RM518)

Reference: REV-31-1410-00

€0.00 (tax incl.)

TRPS1 is a member of the zinc finger family of transcription factors and represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein...

anti-MGB1 (human), Rabbit Monoclonal (RM519)

Reference: REV-31-1411-00

€0.00 (tax incl.)

MGB-1 (Mammaglobin A) is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B....

anti-SV2A, Rabbit Monoclonal (RM520)

Reference: REV-31-1412-00

€0.00 (tax incl.)

SV2A (Synaptic Vesicle protein 2A) is an integral membrane glycoprotein present in synaptic vesicles. SV2s have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A,...

anti-Ki-67 (human), Rabbit Monoclonal (RM521)

Reference: REV-31-1413-00

€0.00 (tax incl.)

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during the late G1, S, G2, and M phases. The protein has a forkhead-associated domain (FHA) through which it...

anti-Delta2-Tubulin, pAb (IN120)

Reference: AG-25B-0044

€0.00 (tax incl.)

Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of α- and β-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different α-...

Category: Primary antibodies

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