Primary antibodies (526)

Phospho-LIMK1-T508 Rabbit pAb

Reference: AP0387

€0.00 (tax incl.)

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually...

Phospho-MEK6-S207 Rabbit pAb

Reference: AP0393

€0.00 (tax incl.)

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs),...

Phospho-NFKB1-S907 Rabbit pAb

Reference: AP0416

€0.00 (tax incl.)

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD...

Phospho-NF-κB2-S870 Rabbit pAb

Reference: AP0419

€0.00 (tax incl.)

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in...

Phospho-IκBα-Y42 Rabbit pAb

Reference: AP0420

€0.00 (tax incl.)

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in...

Phospho-SHP1-Y536 Rabbit pAb

Reference: AP0440

€0.00 (tax incl.)

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,...

Phospho-ZAP70-Y319 Rabbit pAb

Reference: AP0467

€0.00 (tax incl.)

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell...

Phospho-PDK1/PDPK1-S241 Rabbit pAb

Reference: AP0477

€0.00 (tax incl.)

Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Plays a central role in the transduction of signals from insulin by providing the...

Phospho-mTOR-S2481 Rabbit pAb

Reference: AP0490

€0.00 (tax incl.)

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts...

Phospho-Raf1-S338 Rabbit pAb

Reference: AP0498

€0.00 (tax incl.)

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds...

Phospho-JAK2-Y1007/1008 Rabbit pAb

Reference: AP0531

€0.00 (tax incl.)

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for...

Phospho-B-Raf-S728 Rabbit pAb

Reference: AP0576

€0.00 (tax incl.)

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division,...

Phospho-BCR-Y177 Rabbit pAb

Reference: AP0606

€0.00 (tax incl.)

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is...

Phospho-eIF2α-S51 Rabbit mAb

Reference: AP0692

€0.00 (tax incl.)

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of...

Phospho-IκBα-S32 Rabbit pAb

Reference: AP0731

€0.00 (tax incl.)

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in...

Phospho-PKC delta-T505 Rabbit pAb

Reference: AP0776

€0.00 (tax incl.)

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein...

Phospho-PEA15-S104 Rabbit pAb

Reference: AP0788

€0.00 (tax incl.)

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed...

Phospho-AKT1S1/PRAS40-T246 Rabbit pAb

Reference: AP0793

€0.00 (tax incl.)

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]

Phospho-CDK9-T186 Rabbit pAb

Reference: AP0810

€0.00 (tax incl.)

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as...

Phospho-PTPRA-Y789 Rabbit pAb

Reference: AP0814

€0.00 (tax incl.)

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,...

Phospho-PDGFRB-Y1021 Rabbit pAb

Reference: AP0815

€0.00 (tax incl.)

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor...

Phospho-PI3KP85α/γ/β-Y467/Y199/Y464 Rabbit pAb

Reference: AP0854

€0.00 (tax incl.)

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This...

Phospho-IRF3-S386 Rabbit pAb

Reference: AP0857

€0.00 (tax incl.)

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with...

Phospho-STAT1-Y701 Rabbit pAb

Reference: AP0858

€0.00 (tax incl.)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or...

Phospho-STAT5-Y694 Rabbit pAb

Reference: AP0887

€0.00 (tax incl.)

Carries out a dual signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular...

Phospho-IKKα/β-S176/180 Rabbit pAb

Reference: AP0891

€0.00 (tax incl.)

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B...

Phospho-Histone H3-T32 Rabbit pAb

Reference: AP0897

€0.00 (tax incl.)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an...

Phospho-Smad2-T220 Rabbit pAb

Reference: AP0909

€0.00 (tax incl.)

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are...

Phospho-PKM2-Y105 Rabbit pAb

Reference: AP0924

€0.00 (tax incl.)

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein...

Phospho-Raptor-Ser792 Rabbit pAb

Reference: AP0928

€0.00 (tax incl.)

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates...

Phospho-SMO-S611/615 Rabbit pAb

Reference: AP0939

€0.00 (tax incl.)

The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a...

Phospho-MYL9-T18/S19 Rabbit pAb

Reference: AP0955

€0.00 (tax incl.)

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase...

Phospho-p53-S9 Rabbit mAb

Reference: AP0985

€0.00 (tax incl.)

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target...

Phospho-PDHA1-S293 Rabbit mAb

Reference: AP1022

€0.00 (tax incl.)

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between...

Phospho-Src-Y419 Rabbit mAb

Reference: AP1027

€0.00 (tax incl.)

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a...

Phospho-Tau-S396 Rabbit mAb

Reference: AP1028

€0.00 (tax incl.)

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in...

Phospho-HSP27/HSPB1-S82 Rabbit mAb

Reference: AP1031

€0.00 (tax incl.)

The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the...

Phospho-RPA2-T21 Rabbit mAb

Reference: AP1040

€0.00 (tax incl.)

As part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in...

Phospho-β-Catenin-S29/33/37/T41 Rabbit pAb

Reference: AP1076

€0.00 (tax incl.)

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and...

Phospho-α-Synuclein-Y133 Rabbit pAb

Reference: AP1093

€0.00 (tax incl.)

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively....

Phospho-STK3/STK4-T180/T183 Rabbit pAb

Reference: AP1094

€0.00 (tax incl.)

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the...

Phospho-IKKγ-S376 Rabbit pAb

Reference: AP1111

€0.00 (tax incl.)

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other...

Phospho-EGFR-T678 Rabbit pAb

Reference: AP1114

€0.00 (tax incl.)

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface...

Phospho-CDC37-S13 Rabbit mAb

Reference: AP1141

€0.00 (tax incl.)

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction....

Phospho-HSL-S853 Rabbit mAb

Reference: AP1151

€0.00 (tax incl.)

The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts...

Phospho-Paxillin-Y118 Rabbit mAb

Reference: AP1156

€0.00 (tax incl.)

This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different...

Phospho-KRAS-S89 Rabbit pAb

Reference: AP1168

€0.00 (tax incl.)

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating...

Phospho-c-Jun-S63 Rabbit pAb

Reference: AP1190

€0.00 (tax incl.)

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate...

Phospho-MCM2-S139 Rabbit pAb

Reference: AP1192

€0.00 (tax incl.)

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by...

Phospho-alt-RPL36-S19 Rabbit pAb

Reference: AP1209

€0.00 (tax incl.)

Phospho-alt-RPL36-S22 Rabbit pAb

Reference: AP1210

€0.00 (tax incl.)

Phospho-alt-RPL36-S140 Rabbit pAb

Reference: AP1211

€0.00 (tax incl.)

Phospho-IκBα-S32 Rabbit pAb

Reference: AP1220

€0.00 (tax incl.)

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in...

Phospho-NF2-S518 Rabbit pAb

Reference: AP1225

€0.00 (tax incl.)

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product...

Phospho-TAK1-T184/T187 Rabbit pAb

Reference: AP1227

€0.00 (tax incl.)

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety...

Phospho-HSL-S660 Rabbit pAb

Reference: AP1242

€0.00 (tax incl.)

The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts...

Phospho-ATR-T1989 Rabbit pAb

Reference: AP1248

€0.00 (tax incl.)

The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with...

Phospho-GSK3β-S9 Mouse mAb

Reference: AP1258

€0.00 (tax incl.)

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation....

Phospho-Ezrin-Thr567/Radixin-Thr564/Moesin-Thr558 Rabbit pAb

Reference: AP1284

€0.00 (tax incl.)

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between...

Phospho-HER2/ErbB2-Y1139 Rabbit mAb

Reference: AP1285

€0.00 (tax incl.)

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it...

Phospho-Histone H3.3-S31 Rabbit mAb

Reference: AP1296

€0.00 (tax incl.)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer,...

Phospho-p38 MAPK-T180/Y182 Rabbit mAb

Reference: AP1311

€0.00 (tax incl.)

This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation,...

Phospho-Smad5-S463/S465 Rabbit pAb

Reference: AP1319

€0.00 (tax incl.)

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is...

Phospho-S6 Ribosomal Protein (RPS6)-S235/236 Rabbit mAb

Reference: AP1326

€0.00 (tax incl.)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct...

Phospho-JNK1-T183/Y185 + JNK2-T183/Y185 + JNK3-T221/Y223 Rabbit mAb

Reference: AP1337

€0.00 (tax incl.)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as...

Phospho-MEK1/MEK2-S217/S221 Rabbit mAb

Reference: AP1349

€0.00 (tax incl.)

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated...

Phospho-eIF4EBP1-S65 Rabbit mAb

Reference: AP1363

€0.00 (tax incl.)

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit...

Category: Primary antibodies

Menu

Settings