Category: Cell Culture

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Reference: DIV031

Our Nanoparticle Reagent for Protein Targeted Delivery, leveraging lipid nanoemulsions, is a cornerstone in protein cell internalization. Designed for precision biomedicine and therapeutic evaluation, it facilitates protein delivery with minimal cytotoxicity, ensuring the preservation of protein structure and function. Researchers in protein engineering, targeted therapies, and regenerative medicine benefit from this reagent's efficiency in cellular and molecular biology. DIVERSA’S lipid nanoparticles can avoid tedious cell transfection experiments, ensuring constant intracellular levels of the associated and delivered proteins upon simply addition of the formulation into the cell culture medium. DIVERSA can offer customized solutions with a bioluminescent luciferase for cell tracking. DIVERSA’s lipid nanoparticles can be adapted to various administration routes, facilitating seamless translation from in vitro to in vivo settings, achieved through the development of customized solutions.

Reference: MEM-XA

Minimum Essential Medium (MEM) is one of the most frequently used cell culture medium. It is suitable for a variety of adherent or suspension cell types.

Reference: DIV031F1

The Fluorescent Nanoparticle Reagent for Protein Delivery is a breakthrough in protein therapeutics and fluorescence imaging. It ensures effective delivery of protein-loaded nanoemulsions, pivotal for research in proteomics, targeted therapy, and cellular biology. Its strong fluorescence at Ex/Em = 495/503 nm is perfect for visualizing protein interactions in live cells, essential in oncology, immunology, and regenerative medicine. If other fluorescent labels were or preference, please ask DIVERSA for a customize solution.

Reference: RPMI-A

RPMI 1640 medium is widely suitable for supporting growth of many cell types. Compared to other media, it has a unique formulation comprising glutathione and high concentrations of vitamins.

Reference: DIV053

Our Nanoparticle Reagent for Precision RNA Therapy Delivery is a cornerstone in gene therapy and molecular biology. It enables efficient mRNA transfection in cells, including primary cultures and organoids. Applications for protein expression and gene function studies, among others, can be expanded for gene editing with a customized solution. These lipid nanoparticles are compatible with a wide range of cell lines, making it valuable in RNA therapeutics, precision medicine, and in vitro/in vivo gene expression studies. They are formulated in a very simple fashion avoiding the use of microfluidics and other complex infrastructure. DIVERSA’s lipid nanoparticles have a narrow size distribution, are highly biocompatible and stable, do not produce cell toxicity, and lead to high expression levels. DIVERSA’S nanoparticles for delivery of different types of oligonucleotices, as for example siRNA, miRNA, circRNA, ASOs ,and more, can be requested as a customized solution. Additionally, we can offer nanoparticles for surface-decoration with specific ligands for selective targeting under request.

Reference: RPMI-HA

RPMI 1640 medium is widely suitable for supporting growth of many cell types. Compared to other media, it has a unique formulation comprising glutathione and high concentrations of vitamins.

Reference: DIV053F1

The Fluorescent Nanoparticle Reagent for RNA Therapy Delivery is a key tool in RNA-based therapeutics and cellular imaging. With a high transfection efficiency, it allows for the tracking of mRNA delivery in live and fixed cells, essential for studies in gene expression, RNA interference, and gene therapy. With its strong fluorescence and rapid cellular uptake, it's indispensable in fields like genetic engineering, personalized medicine, and in vivo imaging. Alternative solutions can be developed under request, including different fluorophores as Cy3, Cy5, Cy7.