Category: Cell Culture

Reference: SI-1000

Harnessing the same gentle reliability as our market-leading DNA Transfection Reagents, we are proud to introduce to you FuGENE® SI, an innovative RNA Transfection reagent engineered for the delivery of siRNA. FuGENE® SI is a 100% synthetic, multi-component transfection reagent designed for the delivery of RNA molecules into eukaryotic cell lines. FuGENE® SI allows researchers to obtain maximum efficiency knockdowns while being more gentle on cells than competitor’s reagents. Request a sample today for your RNA delivery needs and See the Unseen® with FuGENE® SI.

Reference: SI-5000

Harnessing the same gentle reliability as our market-leading DNA Transfection Reagents, we are proud to introduce to you FuGENE® SI, an innovative RNA Transfection reagent engineered for the delivery of siRNA. FuGENE® SI is a 100% synthetic, multi-component transfection reagent designed for the delivery of RNA molecules into eukaryotic cell lines. FuGENE® SI allows researchers to obtain maximum efficiency knockdowns while being more gentle on cells than competitor’s reagents. Request a sample today for your RNA delivery needs and See the Unseen® with FuGENE® SI.

Reference: DIV000F1

These fluorescent nanoparticles are designed for efficient cellular uptake, a key aspect in cellular biology and drug delivery research. Ideal for live cell imaging and therapeutic applications, this reagent ensures rapid internalization in various cell lines, supporting studies in immunology, oncology, and gene therapy. This cell culture reagent also has an application as positive control for exosome research. Its compatibility with fluorescent microscopy, including confocal and flow cytometry, makes it an essential tool in labs focusing on cell internalization, cell tracking, nanomedicine, and development of advanced therapeutics and cell therapies. DIVERSA fluorescent nanoparticles are biocompatible, outperforming other approaches based on inorganic nanoparticles and quantum dots. DIVERSA can customized them with alternative fluorophores as Cy3, Cy5, Cy7; This makes specific cell population labeling possible to and understanding cell to cell interactions, the relation with the immune system, and in vivo fate, among other applications.

Reference: DIV010

Our Nanoparticle Reagent for Small Molecule Delivery revolutionizes drug delivery systems, increasing solubility of hydrophobic compounds and catering amphiphilic and hydrophilic drugs.  This lipid nanoparticles ensure protection against degradation and can enhance biodistribution, crucial for improved pharmacokinetics and drug efficacy. Its application spans across therapeutic fields, with precise in vivo and in vitro uses, including oncology, neurology, and personalized medicine, offering an efficient pathway for intracellular delivery with minimal cytotoxicity. For surface-decorated nanoparticles with specific ligands against biomarkers and targeted delivery, please ask for a customized solution. DIVERSA’s nanoparticles are highly biocompatible and can transport a higher amount of cargo in comparison to liposomes and polymeric nanoparticles.

Reference: DIV010F1

The Fluorescent Nanoparticle Reagent for Small Molecule Delivery is a groundbreaking tool in molecular biology and pharmacology. Its utilization of lipid nanoemulsions allows for high fluorescence and non-toxic cellular uptake, enabling precise tracking of drug internalization. In addition to its pharmaceutical nanotechnology applications, this reagent provides essential insights into drug-cell interactions, making it invaluable for targeted therapy, drug development, and bioimaging. These fluorescent nanoparticles are specially designed for in vitro studies, and can also be of application for cell tracking, DIVERSA can customized them with alternative fluorophores as Cy3, Cy5, Cy7, This can make possible to label specific cell populations and understand cell to cell interactions, the relation with the immune system, and in vivo fate, among other applications.

Reference: DIV042

Our Nanoparticle Reagent for Peptide Delivery, based on biocompatible lipids that ensure an efficient interaction with anionic peptides, is essential for advanced peptide therapeutics and for the development of targeted therapies and advanced therapies. It's optimized for peptides with a negative net charge, playing a crucial role in research areas like proteomics, peptide drug development, and targeted therapy. This reagent supports efficient cellular delivery, maintaining peptide integrity and activity, ideal for innovative peptide-based treatments. These lipid nanoparticle formulations can be adapted to various administration routes, facilitating seamless translation from in vitro to in vivo settings, achieved through the development of customized solutions. Nanoparticle reagents for cationic peptides and hydrohobic peptides can be requested as a customized solution.

Reference: DIV042F1

The Fluorescent Nanoparticle Reagent for Peptide Delivery (anionic and negatively charged) utilizing lipid nanoemulsions, emerges as a key asset in biomolecular engineering and peptide therapeutics. With its high fluorescence and non-toxic cellular uptake, it facilitates real-time tracking of peptide-loaded nanoparticles in live cells, providing critical insights into cellular dynamics, drug delivery, and therapeutic peptides. Researchers in fields like oncology, immunotherapy, and personalized medicine rely on this reagent for precision and efficiency. If other fluorescent labels were of preference, please ask DIVERSA for a customized solution. Fluorescent reagents for cationic peptides and hydrohobic peptides can be requested as a customized solution.

Reference: DIV031

Our Nanoparticle Reagent for Protein Targeted Delivery, leveraging lipid nanoemulsions, is a cornerstone in protein cell internalization. Designed for precision biomedicine and therapeutic evaluation, it facilitates protein delivery with minimal cytotoxicity, ensuring the preservation of protein structure and function. Researchers in protein engineering, targeted therapies, and regenerative medicine benefit from this reagent's efficiency in cellular and molecular biology. DIVERSA’S lipid nanoparticles can avoid tedious cell transfection experiments, ensuring constant intracellular levels of the associated and delivered proteins upon simply addition of the formulation into the cell culture medium. DIVERSA can offer customized solutions with a bioluminescent luciferase for cell tracking. DIVERSA’s lipid nanoparticles can be adapted to various administration routes, facilitating seamless translation from in vitro to in vivo settings, achieved through the development of customized solutions.

Reference: DIV031F1

The Fluorescent Nanoparticle Reagent for Protein Delivery is a breakthrough in protein therapeutics and fluorescence imaging. It ensures effective delivery of protein-loaded nanoemulsions, pivotal for research in proteomics, targeted therapy, and cellular biology. Its strong fluorescence at Ex/Em = 495/503 nm is perfect for visualizing protein interactions in live cells, essential in oncology, immunology, and regenerative medicine. If other fluorescent labels were or preference, please ask DIVERSA for a customize solution.

Reference: DIV053

Our Nanoparticle Reagent for Precision RNA Therapy Delivery is a cornerstone in gene therapy and molecular biology. It enables efficient mRNA transfection in cells, including primary cultures and organoids. Applications for protein expression and gene function studies, among others, can be expanded for gene editing with a customized solution. These lipid nanoparticles are compatible with a wide range of cell lines, making it valuable in RNA therapeutics, precision medicine, and in vitro/in vivo gene expression studies. They are formulated in a very simple fashion avoiding the use of microfluidics and other complex infrastructure. DIVERSA’s lipid nanoparticles have a narrow size distribution, are highly biocompatible and stable, do not produce cell toxicity, and lead to high expression levels. DIVERSA’S nanoparticles for delivery of different types of oligonucleotices, as for example siRNA, miRNA, circRNA, ASOs ,and more, can be requested as a customized solution. Additionally, we can offer nanoparticles for surface-decoration with specific ligands for selective targeting under request.

Reference: DIV053F1

The Fluorescent Nanoparticle Reagent for RNA Therapy Delivery is a key tool in RNA-based therapeutics and cellular imaging. With a high transfection efficiency, it allows for the tracking of mRNA delivery in live and fixed cells, essential for studies in gene expression, RNA interference, and gene therapy. With its strong fluorescence and rapid cellular uptake, it's indispensable in fields like genetic engineering, personalized medicine, and in vivo imaging. Alternative solutions can be developed under request, including different fluorophores as Cy3, Cy5, Cy7.

Reference: abx098880