Pegacaristim Reference: HY-P99815 Pegacaristim is a monoclonal antibody with thrombopoietic activity. Pegacaristim can promote generation of platelets.
Mezagitamab Reference: HY-P99730 Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP).
Cosibelimab Reference: HY-P99833 Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1+ cell lines, including lymphoma cells.
Tanezumab Reference: HY-P99221 Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia.
Organelle Marker Antibody Panel Reference: GTX300001 Poly(ADP-ribosyl)transferase (PARP1) is a chromatin-associated enzyme, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. This antibody is a control for nuclear localization. PARP1 has a molecular weight of 113 kDa._x000D_ _x000D_ Alpha-tubulin is one of the two the major structural components of microtubules, part of the eukaryotic cytoskeleton. The alpha-tubulin 4a subunit is a highly conserved among species. This antibody is a control for cytoplasmic localization. Alpha-tubulin has a molecular weight of 50 kDa._x000D_ _x000D_ Calnexin is a calcium-binding molecular chaperone protein that plays a critical role in N-glycosylation of proteins. Calnexin is localized to the endoplasmic reticulum (ER) and has a predicted molecular weight of 66 kDa._x000D_ _x000D_ Aldo-keto reductase family 7 (AKR7) is an enzyme involved in the detoxification of aldehydes and ketones. It is localized to the golgi apparatus and has a predicted molecular weight of 40 kDa._x000D_ _x000D_ NHP2-like protein 1 is a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It is localized to the nucleolus and has a predicted molecular weight of 14 kDa
Tesnatilimab Reference: HY-P99389 Tesnatilimab is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab can be used in the study of inflammatory bowel disease (IBD).
Ropeginterferon alfa-2b Reference: HY-P99348 Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms.