Talacotuzumab Reference: HY-P99395 Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models.
Cytotoxic T Cell Surface Marker Antibody Panel (FACS) Reference: ARG30162 Cytotoxic T Cell Surface Marker antibody; APC-conjugated CD28 antibody; Biotin-conjugated CD45 antibody; FITC-conjugated CD54 / ICAM1 antibody; CD8 antibody
Gremubamab Reference: HY-P99649 Gremubamab (MEDI3902) is a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody. Gremubamab binds to the PA PcrV protein and Psl exopolysaccharide. Gremubamab has the potential for the research of pseudomonas aeruginosa infections.
Src Family Protein Tyrosine Kinases Antibody Panel Reference: ARG30169 Src Family Protein Tyrosine Kinases antibody; Fyn antibody; Src antibody; CSK antibody; Lck antibody; Lyn antibody
Anti-Mouse IFN gamma Antibody Reference: HY-P99136 Anti-Mouse IFN gamma Antibody is an anti-mouse IFN gamma IgG antibody inhibitor derived from host Armenian Hamster.
Phospho Src Antibody Panel Reference: ARG30170 Phospho Src antibody; Src phospho (Tyr418) antibody; Src phospho (Tyr529) antibody; Src antibody
Timolumab Reference: HY-P99323 Timolumab (BTT1023 ), a recombinant fully human monoclonal antibody that specifically binds VAP-1. Timolumab (BTT1023 ) could be used in the study of chronic inflammatory diseases.
Revdofilimab Reference: HY-P99945 Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells.