Antibodies (3)

anti-Caspase-1 (p10) (Mouse mAb (Casper-2) (Biotin)

Reference: AG-20B-0044B-C100

€0.00 (tax incl.)

Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called...

anti-NAIP1/2/5 (Mouse mAb (Naipa-1)

Reference: AG-20B-0045-C100

€0.00 (tax incl.)

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...

anti-NLRP6/NALP6 (human), mAb (Clint-1)

Reference: AG-20B-0046-C100

€0.00 (tax incl.)

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...

anti-Caspase-1 (p20) (human), mAb (Bally-1)

Reference: AG-20B-0048-C100

€0.00 (tax incl.)

Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called...

anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin)

Reference: AG-20B-0048B-C100

€0.00 (tax incl.)

Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called...

anti-BTLA (human), mAb (6F4)

Reference: AG-20B-0049-C100

€0.00 (tax incl.)

B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs. The herpes virus entry mediator (HVEM), a member of the TNF receptor (TNFR)...

anti-IL-1alpha (Mouse mAb (Bamboo-1)

Reference: AG-20B-0050-C100

€0.00 (tax incl.)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....

anti-Notch1 (Mouse mAb (22E5)

Reference: AG-20B-0051-C100

€0.00 (tax incl.)

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind...

anti-Notch1 (Mouse mAb (22E5) (Biotin)

Reference: AG-20B-0051B-C100

€0.00 (tax incl.)

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind...

anti-Notch2, mAb (16F11)

Reference: AG-20B-0052-C100

€0.00 (tax incl.)

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind...

anti-Notch2, mAb (16F11) (Biotin)

Reference: AG-20B-0052B-C100

€0.00 (tax incl.)

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind...

anti-DLL1 (Mouse mAb (30B11.1)

Reference: AG-20B-0053-C100

€0.00 (tax incl.)

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. It blocks the...

anti-DLL4 (Mouse mAb (9A1.5)

Reference: AG-20B-0054-C100

€0.00 (tax incl.)

The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative...

anti-FLIP (human), mAb (NF6)

Reference: AG-20B-0056-C050

€0.00 (tax incl.)

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment...

anti-FLIP (human), mAb (NF6)

Reference: AG-20B-0056-C100

€0.00 (tax incl.)

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment...

anti-FLIP (human), mAb (NF6) (Biotin)

Reference: AG-20B-0056B-C050

€0.00 (tax incl.)

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment...

anti-Caspase-8 (human), mAb (C15)

Reference: AG-20B-0057-C050

€0.00 (tax incl.)

Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the...

anti-Caspase-8 (human), mAb (C15)

Reference: AG-20B-0057-C100

€0.00 (tax incl.)

Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the...

anti-IL-1alpha (Mouse mAb (Bamboo-2)

Reference: AG-20B-0058-C100

€0.00 (tax incl.)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....

anti-IL-1alpha (Mouse mAb (Bamboo-2) (Biotin)

Reference: AG-20B-0058B-C100

€0.00 (tax incl.)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....

anti-Caspase-4/11 (p20), mAb (Flamy-1)

Reference: AG-20B-0060-C100

€0.00 (tax incl.)

Inflammatory caspases (also known as group I caspases) are encoded by three main genes in humans, caspase-1, caspase-4 and caspase-5 and three main genes in mouse, caspase-1, caspase-11 and caspase-12. Caspase-11 is...

anti-Caspase-4/11 (p20), mAb (Flamy-1) (Biotin)

Reference: AG-20B-0060B-C100

€0.00 (tax incl.)

Inflammatory caspases (also known as group I caspases) are encoded by three main genes in humans, caspase-1, caspase-4 and caspase-5 and three main genes in mouse, caspase-1, caspase-11 and caspase-12. Caspase-11 is...

anti-Fas (human), mAb (APO-1-3) (preservative free)

Reference: AG-20B-0062PF-C050

€0.00 (tax incl.)

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas...

anti-Fas (human), mAb (APO-1-3) (preservative free)

Reference: AG-20B-0062PF-C100

€0.00 (tax incl.)

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas...

anti-Fas (human), mAb (APO-1-3) (preservative free)

Reference: AG-20B-0062PF-C500

€0.00 (tax incl.)

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas...

anti-BAFF (Mouse mAb (blocking) (Sandy-2)

Reference: AG-20B-0063-C100

€0.00 (tax incl.)

BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF...

anti-BAFF (Mouse mAb (blocking) (Sandy-2) (preservative free)

Reference: AG-20B-0063PF-C100

€0.00 (tax incl.)

BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF...

anti-BAFF (Mouse mAb (blocking) (Sandy-2) (preservative free)

Reference: AG-20B-0063PF-C500

€0.00 (tax incl.)

BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF...

anti-IL-1alpha (p18) (Mouse mAb (Teo-1)

Reference: AG-20B-0064-C100

€0.00 (tax incl.)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....

anti-ZAG (human), mAb (Zagy-1)

Reference: AG-20B-0065-C100

€0.00 (tax incl.)

Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in...

anti-ZAG (human), mAb (Zagy-2)

Reference: AG-20B-0066-C100

€0.00 (tax incl.)

Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in...

anti-NLRC3 (Mouse mAb (Eowyn-1)

Reference: AG-20B-0067-C100

€0.00 (tax incl.)

The novel nucleotide oligomerization domain (NOD)-like receptor (NLR) with a caspase activation and recruitment domain (CARD) 3 (NLRC3) protein belongs to the NLR family of cytosolic pathogen recognition receptors....

anti-alpha-Tubulin (acetylated), mAb (TEU318)

Reference: AG-20B-0068-C100

€0.00 (tax incl.)

Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of...

anti-IL-36beta (human), mAb (Jacky-1)

Reference: AG-20B-0069-C100

€0.00 (tax incl.)

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines,...

anti-IL-38, mAb (Nhat-1)

Reference: AG-20B-0070-C100

€0.00 (tax incl.)

IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a...

anti-MPC-2, mAb (JCM-1)

Reference: AG-20B-0071-C100

€0.00 (tax incl.)

Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize...

anti-IL-36gamma (human), mAb (Jussy-1)

Reference: AG-20B-0072-C100

€0.00 (tax incl.)

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines...

anti-Asprosin, mAb (Birdy-1)

Reference: AG-20B-0073-C100

€0.00 (tax incl.)

Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white...

anti-Asprosin (human), mAb (Birdy-2)

Reference: AG-20B-0074-C100

€0.00 (tax incl.)

Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white...

anti-PD-1 (Mouse mAb (blocking) (1H10)

Reference: AG-20B-0075-C100

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

anti-PD-1 (Mouse mAb (blocking) (1H10) (preservative free)

Reference: AG-20B-0075PF-C100

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

anti-PD-1 (Mouse mAb (blocking) (1H10) (preservative free)

Reference: AG-20B-0075PF-C500

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

anti-PD-1 (Mouse mAb (blocking) (1H10) (preservative free)

Reference: AG-20B-0075PF-M002

€0.00 (tax incl.)

CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4...

anti-Resistin (human), mAb (HRES106)

Reference: AG-20B-0076-C100

€0.00 (tax incl.)

The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMα/FIZZ 1 and RELMβ/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be...

anti-Resistin (Mouse mAb (MRES18)

Reference: AG-20B-0077-C100

€0.00 (tax incl.)

The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMα/FIZZ 1 and RELMβ/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be...

anti-APRIL (human), mAb (blocking) (Mahya-1) (preservative free)

Reference: AG-20B-0078PF-C100

€0.00 (tax incl.)

The B cell-stimulating molecules, BAFF (B cell activating factor) and APRIL (a proliferation-inducing ligand), are critical factors in the maintenance of the B cell pool and humoral immunity. APRIL binds to...

anti-APRIL (human), mAb (blocking) (Mahya-1) (preservative free)

Reference: AG-20B-0078PF-C500

€0.00 (tax incl.)

The B cell-stimulating molecules, BAFF (B cell activating factor) and APRIL (a proliferation-inducing ligand), are critical factors in the maintenance of the B cell pool and humoral immunity. APRIL binds to...

anti-Fas (human), mAb (APO-1-1) (preservative free)

Reference: AG-20B-0079PF-C100

€0.00 (tax incl.)

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas...

anti-Fas (human), mAb (APO-1-1) (preservative free)

Reference: AG-20B-0079PF-C500

€0.00 (tax incl.)

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas...

anti-FADD (human), mAb (1C4)

Reference: AG-20B-0080-C100

€0.00 (tax incl.)

FADD (FAS-associated death domain protein) is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. Procaspase-8 belongs to the family of caspases....

anti-FADD (human), mAb (1C4) (Biotin)

Reference: AG-20B-0080B-C100

€0.00 (tax incl.)

FADD (FAS-associated death domain protein) is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. Procaspase-8 belongs to the family of caspases....

anti-TNF-alpha (Mouse mAb (blocking) (V1q) (preservative free)

Reference: AG-20B-0081PF-C100

€0.00 (tax incl.)

Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-α) is a cytokine involved in systemic inflammation and metabolism and is a member of a group of cytokines that stimulate...

anti-TNF-alpha (Mouse mAb (blocking) (V1q) (preservative free)

Reference: AG-20B-0081PF-C500

€0.00 (tax incl.)

Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-α) is a cytokine involved in systemic inflammation and metabolism and is a member of a group of cytokines that stimulate...

anti-Periostin, mAb (blocking) (OC-20) (preservative free)

Reference: AG-20B-6000PF-C100

€0.00 (tax incl.)

Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are...

anti-Fibronectin (EDA), mAb (blocking) (IST-9) (preservative free)

Reference: AG-20B-6001PF-C100

€0.00 (tax incl.)

Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and...

anti-Lewis y/b hapten (human), mAb (SC104) (preservative free)

Reference: AG-20B-6002PF-C100

€0.00 (tax incl.)

Membrane glycolipids represent an unexplored source of tumor-associated antigens. Many of these are overexpressed and altered in tumors compared to normal tissue. Research into aberrant glycosylation and...

anti-PD-1 (human), mAb (AG-IHC001)

Reference: AG-20B-6020-R100

€0.00 (tax incl.)

Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the...

anti-PD-1 (human), mAb (AG-IHC001)

Reference: AG-20B-6020-L001

€0.00 (tax incl.)

Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the...

anti-Tim-3 (human), mAb (AG-IHC003)

Reference: AG-20B-6021-R100

€0.00 (tax incl.)

T cell Immunoglobulin and Mucin Domain-containing Molecule-3 (TIM-3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM-3 is overexpressed in CD4+...

anti-Tim-3 (human), mAb (AG-IHC003)

Reference: AG-20B-6021-L001

€0.00 (tax incl.)

T cell Immunoglobulin and Mucin Domain-containing Molecule-3 (TIM-3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM-3 is overexpressed in CD4+...

anti-PD-L1 (human), mAb (AG-IHC411)

Reference: AG-20B-6022-R100

€0.00 (tax incl.)

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. PD-L1 is a transmembrane protein...

anti-PD-L1 (human), mAb (AG-IHC411)

Reference: AG-20B-6022-L001

€0.00 (tax incl.)

Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. PD-L1 is a transmembrane protein...

anti-LAG-3 (human), mAb (AG-IHC103)

Reference: AG-20B-6023-R100

€0.00 (tax incl.)

LAG-3 is a cell surface molecule expressed by activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. It binds to major histocompatibility complex (MHC) class II molecules and serves as an...

anti-LAG-3 (human), mAb (AG-IHC103)

Reference: AG-20B-6023-L001

€0.00 (tax incl.)

LAG-3 is a cell surface molecule expressed by activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. It binds to major histocompatibility complex (MHC) class II molecules and serves as an...

anti-Isocitrate Dehydrogenase 1 [IDH1] (R132H Mutant) (human), mAb (AG-IHC132)

Reference: AG-20B-6024-R100

€0.00 (tax incl.)

Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and...

anti-Isocitrate Dehydrogenase 1 [IDH1] (R132H Mutant) (human), mAb (AG-IHC132)

Reference: AG-20B-6024-L001

€0.00 (tax incl.)

Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and...

anti-Arginase I (human), mAb (AG-IHC400)

Reference: AG-20B-6025-R100

€0.00 (tax incl.)

Arginase I, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea....

anti-Arginase I (human), mAb (AG-IHC400)

Reference: AG-20B-6025-L001

€0.00 (tax incl.)

Arginase I, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea....

anti-Poly(ADP-ribose) [PAR], mAb (10H)

Reference: AG-20T-0001-C050

€0.00 (tax incl.)

Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair...

anti-Poly(ADP-ribose) [PAR], mAb (10H)

Reference: AG-20T-0001-C100

€0.00 (tax incl.)

Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair...

anti-Poly(ADP-ribose) [PAR], mAb (10H)

Reference: AG-20T-0001-M001

€0.00 (tax incl.)

Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair...

anti-VASP, mAb (IE273)

Reference: AG-20T-0002-C050

€0.00 (tax incl.)

VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on...

anti-Survival Motor Neuron Protein, mAb (7B10)

Reference: AG-20T-0003-C200

€0.00 (tax incl.)

The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. It is expressed in a...

anti-PARP-10 [ARTD10] (human), mAb (5H11)

Reference: AG-20T-0004-L001

€0.00 (tax incl.)

PARP-10 is a mono-ADP-ribosyltransferase and was initially identified as an interaction partner of the proto-oncoprotein Myc. PARP-10 possesses ubiquitin-interaction motifs, which are important to inhibit the...

anti-Podoplanin (human), mAb (18H5)

Reference: AG-20T-0100-C100

€0.00 (tax incl.)

Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular...

anti-Podoplanin (Mouse mAb (RTD4E10)

Reference: AG-20T-0101-C100

€0.00 (tax incl.)

Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular...

anti-TIE-2 (human), mAb (tek2)

Reference: AG-20T-0102-C100

€0.00 (tax incl.)

TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton,...

anti-TIE-2 (human), mAb (tek9)

Reference: AG-20T-0103-C100

€0.00 (tax incl.)

TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton,...

anti-TIE-2 (human), mAb (tek16)

Reference: AG-20T-0104-C100

€0.00 (tax incl.)

TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton,...

anti-VEGF-A (human), mAb (3(6D3))

Reference: AG-20T-0105-C200

€0.00 (tax incl.)

Human vascular endothelial erowth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF-A is a specific mitogen for vascular endothelial...

anti-VEGFR-1 (human), mAb (EWC)

Reference: AG-20T-0106-C100

€0.00 (tax incl.)

Recombinant human soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) is the naturally occurring form and is a glycosylated monomeric protein. The biological function of sVEGFR-1 seems to be an endogenous...

anti-VEGFR-1 (human), mAb (EWF)

Reference: AG-20T-0107-C100

€0.00 (tax incl.)

Recombinant human soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) is the naturally occurring form and is a glycosylated monomeric protein. The biological function of sVEGFR-1 seems to be an endogenous...

anti-VEGFR-2/KDR (human), mAb (EIC)

Reference: AG-20T-0108-C100

€0.00 (tax incl.)

Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been...

anti-VEGFR-2/KDR (human), mAb (3(4H3))

Reference: AG-20T-0109-C100

€0.00 (tax incl.)

Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been...

anti-Bmf, mAb (9G10)

Reference: AG-20T-0130-C100

€0.00 (tax incl.)

Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...

anti-Bmf (mouse/rat), mAb (17A9)

Reference: AG-20T-0131-C100

€0.00 (tax incl.)

Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...

anti-Apaf-1 (human), mAb (2E12)

Reference: AG-20T-0132-C100

€0.00 (tax incl.)

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short...

anti-Apaf-1 (mouse/rat), mAb (13F11)

Reference: AG-20T-0133-C100

€0.00 (tax incl.)

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short...

anti-Apaf-1, mAb (18H2)

Reference: AG-20T-0134-C100

€0.00 (tax incl.)

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short...

anti-Caspase-2, mAb (10C6)

Reference: AG-20T-0135-C100

€0.00 (tax incl.)

Caspase-2 is a Class I caspase with a long prodomain necessary for nuclear localization. Upon activation of the apoptotic pathway, the procaspase is cleaved into smaller fragments. Caspase-2 is the nuclear apoptotic...

anti-Caspase-2, mAb (11B4)

Reference: AG-20T-0136-C100

€0.00 (tax incl.)

Caspase-2 is a Class I caspase with a long prodomain necessary for nuclear localization. Upon activation of the apoptotic pathway, the procaspase is cleaved into smaller fragments. Caspase-2 is the nuclear apoptotic...

anti-Caspase-8 (Mouse mAb (1G12)

Reference: AG-20T-0137-C100

€0.00 (tax incl.)

Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the...

anti-Caspase-8 (Mouse mAb (3B10)

Reference: AG-20T-0138-C100

€0.00 (tax incl.)

Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the...

anti-Caspase-11 (Mouse mAb (8A5)

Reference: AG-20T-0139-C100

€0.00 (tax incl.)

Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular...

anti-Caspase-11 (Mouse mAb (4E11)

Reference: AG-20T-0140-C100

€0.00 (tax incl.)

Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular...

anti-Caspase-12 (Mouse mAb (12G6)

Reference: AG-20T-0141-C100

€0.00 (tax incl.)

Caspase-12 is a member of the ICE/CED-3 family of caspases and is detected as a protein of ~51kDa. Overexpression of caspase-12 in cells induces apoptosis. Capase-12 is localized to the endoplasmatic reticulum (ER)...

anti-BimS/EL/L, mAb (3C5)

Reference: AG-20T-0142-C100

€0.00 (tax incl.)

Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a...

anti-BimS/EL/L, mAb (10B12)

Reference: AG-20T-0143-C100

€0.00 (tax incl.)

Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a...

anti-TLR2, mAb (ABM3A87)

Reference: AG-20T-0300-C100

€0.00 (tax incl.)

TLR2 (Toll-like Receptor 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 acts via MYD88 and TRAF6, leading to...

anti-TLR2, mAb (ABM3A87) (APC)

Reference: AG-20T-0300C-C100

€0.00 (tax incl.)

TLR2 (Toll-like Receptor 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 acts via MYD88 and TRAF6, leading to...

Category: Antibodies

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