Rabbit anti-Human IL-8 mAb (DET) Reference: RM17649 IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Rabbit anti-Human IL-6 mAb (CAP) Reference: RM17650 Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates "classic signaling", whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Rabbit anti-Human IL-6 mAb (DET) Reference: RM17651 Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates "classic signaling", whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Rabbit anti-Human IL-6 mAb (DET) Reference: RM17652 Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates "classic signaling", whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Rabbit anti-Human cTnI mAb (CAP) Reference: RM17653 Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity
Rabbit anti-Human cTnI mAb (DET) Reference: RM17654 Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity