Pertuzumab (PBS) Reference: HY-P9912A Pertuzumab (PBS), a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
oYo-Link® DBCO Antibody Labeling Kit - Labels 100ug Reference: AT3003-100 NOTE: It is important to perform the click-reaction with Azide-x first, prior to antibody conjugation. UV illumination will damage the DBCO activity and thus antibody conjugation should only be performed after the click-reaction. Research Use Only Applications: Copper-free Click Chemistry oYo-Link® DBCO allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two dibenzocyclooctyne (DBCO) labels per antibody for subsequent copper-free click chemistry reactions. oYo-Link®-DBCO limits the attachment of the DBCO labels to the heavy chains of the antibody and therefore ensures that the DBCO label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 DBCO labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® -DBCO with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list here or purchase AlphaThera's LED Photo-Crosslinking Device Here. Purchasing Information: For Credit Card purchases, proceed with checkout on website. To Request a Quote email sales@alphathera.com. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
Izalontamab Reference: HY-P99676 Izalontamab (SI-B001) is a bispecific anti-EGFR/HER3 monoclonal antibody with high selectivity for EGFR/HER3 heterodimer. Izalontamab can be used for the research of cancer.
oYo-Link® DBCO Antibody Labeling Kit- Labels 500ug Reference: AT3003-500 NOTE: It is important to perform the click-reaction with Azide-x first, prior to antibody conjugation. UV illumination will damage the DBCO activity and thus antibody conjugation should only be performed after the click-reaction. Research Use Only Applications: Copper-free Click Chemistry oYo-Link® DBCO allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two dibenzocyclooctyne (DBCO) labels per antibody for subsequent copper-free click chemistry reactions. oYo-Link®-DBCO limits the attachment of the DBCO labels to the heavy chains of the antibody and therefore ensures that the DBCO label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 DBCO labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® -DBCO with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list here or purchase AlphaThera's LED Photo-Crosslinking Device Here. Purchasing Information: For Credit Card purchases, proceed with checkout on website. To Request a Quote email sales@alphathera.com. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
hMC1R agonist 1 Reference: HY-P99004 (EC50=3 nM). hMC1R agonist 1 shows at least 300-fold selectivity for hMC1R over hMC3R (b>EC50=902 nM), hMC4R (b>EC50=915 nM), and hMC5R (b>EC50=>1000 nM). hMC1R agonist 1 has the potential for the therapeutic intervention of melanocortin family.
oYo-Link® DBCO Antibody Labeling Kit - Labels 1mg Reference: AT3003-1000 NOTE: It is important to perform the click-reaction with Azide-x first, prior to antibody conjugation. UV illumination will damage the DBCO activity and thus antibody conjugation should only be performed after the click-reaction. Research Use Only Applications: Copper-free Click Chemistry oYo-Link® DBCO allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two dibenzocyclooctyne (DBCO) labels per antibody for subsequent copper-free click chemistry reactions. oYo-Link®-DBCO limits the attachment of the DBCO labels to the heavy chains of the antibody and therefore ensures that the DBCO label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 DBCO labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® -DBCO with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list here or purchase AlphaThera's LED Photo-Crosslinking Device Here. Purchasing Information: For Credit Card purchases, proceed with checkout on website. To Request a Quote email sales@alphathera.com. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
Izenivetmab Reference: HY-P99677 Izenivetmab (ZTS-00075623) is a caninized IgG2κ anti-NGFB monoclonal antibody.
oYo-Link® DBCO Antibody Labeling Kit - Labels 100ug mIgG1 Ab Reference: AT3003-mIgG1-100 NOTE: It is important to perform the click-reaction with Azide-x first, prior to antibody conjugation. UV illumination will damage the DBCO activity and thus antibody conjugation should only be performed after the click-reaction. Research Use Only Applications: Copper-free Click Chemistry oYo-Link® DBCO allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two dibenzocyclooctyne (DBCO) labels per antibody for subsequent copper-free click chemistry reactions. oYo-Link®-DBCO limits the attachment of the DBCO labels to the heavy chains of the antibody and therefore ensures that the DBCO label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 DBCO labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® -DBCO with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list here or purchase AlphaThera's LED Photo-Crosslinking Device Here. Purchasing Information: For Credit Card purchases, proceed with checkout on website. To Request a Quote email sales@alphathera.com. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com