Nogapendekin alfa Reference: HY-P99759 Nogapendekin alfa is a superagonist of IL-15. Nogapendekin alfa promotes the proliferation and viability of immune cells. Nogapendekin alfa combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form ALT-803, an IL-15 cytokine antibody fusion protein. ALT-803 reduces tumor burden by activation of NK cells and CD8+ T cells.
oYo-Link® Tetrazine Antibody Labeling Kit - Labels 1mg Reference: AT3004-1000 Research Use Only Applications: Click Chemistry with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two tetrazine labels per antibody for subsequent copper-free click chemistry reactions with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine limits the attachment of the tetrazine labels to the heavy chains of the antibody and therefore ensures that the tetrazine label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 tetrazine labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® Tetrazine with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from our list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
Frovocimab Reference: HY-P99626 Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9. Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact PCSK9.
oYo-Link® Tetrazine Antibody Labeling Kit - Labels 100ug mIgG1 Ab Reference: AT3004-mIgG1-100 Research Use Only Applications: Click Chemistry with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two tetrazine labels per antibody for subsequent copper-free click chemistry reactions with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine limits the attachment of the tetrazine labels to the heavy chains of the antibody and therefore ensures that the tetrazine label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 tetrazine labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® Tetrazine with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from our list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
Urelumab Reference: HY-P99055 Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab. Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL).
oYo-Link® Tetrazine Antibody Labeling Kit- Labels 500ug mIgG1 Ab Reference: AT3004-mIgG1-500 Research Use Only Applications: Click Chemistry with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine allows for the site-specific labeling of oYo-Link®-compatible antibodies with up to two tetrazine labels per antibody for subsequent copper-free click chemistry reactions with TCO (trans-cyclooctene)-bound molecules. oYo-Link® Tetrazine limits the attachment of the tetrazine labels to the heavy chains of the antibody and therefore ensures that the tetrazine label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 tetrazine labels to be attached per antibody, providing precise antibody-conjugate ratios. The antibody labeling procedure simply requires mixing oYo-Link® Tetrazine with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from our list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility or click-chemistry procedure email support@alphathera.com
Ascrinvacumab Reference: HY-P99353 Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC).
oYo-Link® Single-Biotin Antibody Labeling Kit - Labels 100ug Reference: AT4001-100 Research Use Only Applications: Conjugation of capture antibodies for Streptavidin-Coated Surface Immobilization in Direct ELISA; Also for Sandwich-ELISA oYo-Link® Single-Biotin is recommended for the immobilization of antibodies on Streptavidin-coated surfaces (or coated w/ other biotin-binding proteins). oYo-Link® Single-Biotin enables the site-specific labeling of oYo-Link®-compatible antibodies with a biotin to the IgG heavy chain. The use of a single biotin maximizes mobility and antigen binding density of surface-immobilized antibodies. Site-specific immobilization can lead to an improvement in sensitivity, stability and longevity of capture antibodies. While the magnitude of improvement is dependent on various parameters, such as antibody binding properties, uniform antibody orientation on a surface can result in an increase in sensitivity in enzyme-linked immunosorbent assays (ELISA) by enabling the capture of more antigens per unit area. The antibody labeling procedure simply requires mixing oYo-Link® Single-Biotin with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility email support@alphathera.com
Telazorlimab Reference: HY-P99570 Telazorlimab (GBR-830) is a humanized monoclonal antibody against OX40 costimulatory receptor on activated T cells. Telazorlimab can be used for the research of autoimmune diseases.
oYo-Link® Single-Biotin Antibody Labeling Kit- Labels 500ug Reference: AT4001-500 Research Use Only Applications: Conjugation of capture antibodies for Streptavidin-Coated Surface Immobilization in Direct ELISA; Also for Sandwich-ELISA oYo-Link® Single-Biotin is recommended for the immobilization of antibodies on Streptavidin-coated surfaces (or coated w/ other biotin-binding proteins). oYo-Link® Single-Biotin enables the site-specific labeling of oYo-Link®-compatible antibodies with a biotin to the IgG heavy chain. The use of a single biotin maximizes mobility and antigen binding density of surface-immobilized antibodies. Site-specific immobilization can lead to an improvement in sensitivity, stability and longevity of capture antibodies. While the magnitude of improvement is dependent on various parameters, such as antibody binding properties, uniform antibody orientation on a surface can result in an increase in sensitivity in enzyme-linked immunosorbent assays (ELISA) by enabling the capture of more antigens per unit area. The antibody labeling procedure simply requires mixing oYo-Link® Single-Biotin with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility email support@alphathera.com
Tremelimumab Reference: HY-P9918 Tremelimumab (Ticilimumab) is a fully humanized monoclonal antibody specific for cytotoxic T-lymphocyte antigen-4 (CTLA-4) and can be used for metastatic melanoma research.
oYo-Link® Single-Biotin Antibody Labeling Kit - Labels 1mg Reference: AT4001-1000 Research Use Only Applications: Conjugation of capture antibodies for Streptavidin-Coated Surface Immobilization in Direct ELISA; Also for Sandwich-ELISA oYo-Link® Single-Biotin is recommended for the immobilization of antibodies on Streptavidin-coated surfaces (or coated w/ other biotin-binding proteins). oYo-Link® Single-Biotin enables the site-specific labeling of oYo-Link®-compatible antibodies with a biotin to the IgG heavy chain. The use of a single biotin maximizes mobility and antigen binding density of surface-immobilized antibodies. Site-specific immobilization can lead to an improvement in sensitivity, stability and longevity of capture antibodies. While the magnitude of improvement is dependent on various parameters, such as antibody binding properties, uniform antibody orientation on a surface can result in an increase in sensitivity in enzyme-linked immunosorbent assays (ELISA) by enabling the capture of more antigens per unit area. The antibody labeling procedure simply requires mixing oYo-Link® Single-Biotin with the desired antibody followed by photocrosslinking with non-damaging black light (365 nm). Photocrosslinking can be carried out in most buffers, including those containing amine-containing molecules (e.g. TRIS, glycine) or storage proteins (see Buffer Compatibility Table). Requirements: To label your compatible antibodies with oYo-Link®, you will need a Light Source emitting at 365nm (6-10W). Use your own Compatible Device from the list or purchase AlphaThera's LED Photo-Crosslinking Device. Technical Support: For questions concerning compatibility email support@alphathera.com