Apoptosis, the physiological process of cell death, is a naturally occurring phenomenon. It is normally a tightly regulated process; however, if deregulated, tumor growth can result. Apoptotic processes can be...
Apoptosis, the physiological process of cell death, is a naturally occurring phenomenon. It is normally a tightly regulated process; however, if deregulated, tumor growth can result. Apoptotic processes can be...
AlphaGrow™ SF Hybridoma is the industries’ premier serum free cell culture media for the growth
of hybridoma cells and production of monoclonal antibodies in serum free cultures without forfeiting
cell viability or...
AlphaGrow™ SF Hybridoma is the industries’ premier serum free cell culture media for the growth
of hybridoma cells and production of monoclonal antibodies in serum free cultures without forfeiting
cell viability or...
Many cell types such as monocytes, granulocytes, B cells and dendritic cells express Fc receptors (FcRs) on their surfaces (See Table 1). FcR-mediated IgFc binding can negatively affect the results of...
Many cell types such as monocytes, granulocytes, B cells and dendritic cells express Fc receptors (FcRs) on their surfaces (See Table 1). FcR-mediated IgFc binding can negatively affect the results of...
Apoptosis, the physiological process of cell death, is a naturally occurring phenomenon. It is normally a tightly regulated process; however, if deregulated, tumor growth can result. Apoptotic processes can be...
Apoptosis, the physiological process of cell death, is a naturally occurring phenomenon. It is normally a tightly regulated process; however, if deregulated, tumor growth can result. Apoptotic processes can be...
Chinese authorities identified an outbreak caused by a novel—or new—coronavirus termed SARS-CoV-2. The virus can cause mild to severe respiratory illness; known as Coronavirus Disease 2019 (COVID-19) formerly called...
Apoptosis, the physiological process of cell death, is a naturally occurring phenomenon. It is normally a tightly regulated process; however, if deregulated, tumor growth can result. Apoptotic processes can be...
Interleukin 13 (IL-13) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells1, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a...
Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking...
Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. M-CSF is a key regulator of cellular...
Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine1 is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of...
RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine1 is an important mediators of the immune and inflammatory response.2 It is also a potent chemoattractant for T cells 3 and eosinophils.4...
CD120 can refer to two members of the tumor necrosis factor receptor superfamily- CD120a (TNFR1) or CD120b (TNFR2). CD120a is a 55kD Type I transmembrane protein receptor that binds both TNF-α and TNF-β (LT-α). In...
Leptin is a neuroendocrine hormone secreted from adipose tissue that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Leptin is one of the most important adipose...
Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as G-CSF colony-stimulating factor 3 (CSF 3) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a...
The CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.1 Eotaxin and related molecules are potentially important...
CD120 can refer to two members of the tumor necrosis factor receptor superfamily- CD120a (TNFR1) or CD120b (TNFR2). CD120a is a 55kD Type I transmembrane protein receptor that binds both TNF-α and TNF-β (LT-α). In...
IL-17F is a homodimeric protein that is a member of the IL17 family of cytokines produced by activated T-cells and monocytes.1 IL-17F is expressed by activated T cells and can stimulate production of other cytokines...
RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine1 is an important mediators of the immune and inflammatory response.2 It is also a potent chemoattractant for T cells 3 and eosinophils.4...
Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles. IL-8 is one of the...
Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine with mitogenic properties belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3)...
IL-3 is a 17 kD pleiotropic cytokine and a member of a family of growth factors that sustains both the proliferation and the development of hematopoietic precursors. It also displays neurotrophic activity and is...
Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as G-CSF colony-stimulating factor 3 (CSF 3) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a...
Chinese authorities identified an outbreak caused by a novel—or new—coronavirus termed SARS-CoV-2. The virus can cause mild to severe respiratory illness; known as Coronavirus Disease 2019 (COVID-19) formerly called...
Nerve growth factor beta (NGF-beta) is a secreted protein that is important for the differentiation and survival of neurons and dermal keratinocytes.1 It is also involved in cell proliferation and survival, and it is...
Monocyte chemotactic protein-1 (MCP-1) is an essential chemokine produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes.1,2,3 It can induce the proliferation and...
Monocyte chemotactic protein-1 (MCP-1) is an essential chemokine produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes.1,2,3 It can induce the proliferation and...
Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family. CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes,...
Interleukin 13 (IL-13) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells1, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a...
Interleukin-10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is a homodimer protein produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic...
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other...
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other...
Interleukin-4 (IL-4) is a pleiotropic immune cytokine secreted by activated Th2 cells that inhibits bone resorption.1 IL-4 is critical for inducing allergic responses.2 It has many biological roles, including the...
Macrophage inflammatory protein 1 alpha (MIP-1 alpha) is a potent inhibitor of hemopoietic stem cell proliferation and is a member of a family of pro- inflammatory mediators, the chemokine family.1 MIP-1 alpha is a...
Interleukin-2 (IL-2) is a potent T-cell mitogenic cytokine1 that functions as a primary regulator of T cell homeostasis and has been considered a prime candidate immunotherapeutics, both for increasing T cell...
Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated...
Macrophage inflammatory protein 1 alpha (MIP-1 alpha) is a potent inhibitor of hemopoietic stem cell proliferation and is a member of a family of pro- inflammatory mediators, the chemokine family.1 MIP-1 alpha is a...
Chemokine (C-X-C motif) ligand 2 (CXCL2) is an inducible murine chemokine involved in attraction of polymorphonuclear granulocytes to sites of infection.1 This chemokine is secreted by monocytes and macrophages and is...
Acidic and basic fibroblast growth factors (FGFs) are members of a family of proteins that exert pleiotropic effects in a range of cell types including skeletal myocytes.1 Fibroblast growth factor basic (FGF basic)...
BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in...
Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine1 is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of...
The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity.1 It may mediate some of the significant changes in cellular homeostasis which accompany...
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and...
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.2 It is a cytokine critical for innate and adaptive immunity against viral and...
Interleukin-10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is a homodimer protein produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic...
Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is the main factor that promotes the terminal...
Interleukin-4 (IL-4) is a pleiotropic immune cytokine secreted by activated Th2 cells that inhibits bone resorption.1 IL-4 is critical for inducing allergic responses.2 It has many biological roles, including the...
Interleukin-2 (IL-2) is a potent T-cell mitogenic cytokine1 that functions as a primary regulator of T cell homeostasis and has been considered a prime candidate immunotherapeutics, both for increasing T cell...
Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the...
Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the...
Human GM-CSF ELISA development kit is designed for the quantitative measurement within the range of 32-3000 pg/ml of natural or recombinant GM-CSF. Granulocyte-Macrophage Colony Stimulating Factor is a 22 kD,...
Human GM-CSF ELISA development kit is designed for the quantitative measurement within the range of 32-3000 pg/ml of natural or recombinant GM-CSF. Granulocyte-Macrophage Colony Stimulating Factor is a 22 kD,...
Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR.1 EGF acts by binding with high...