KRISHZYME™ Heparin Factor Xa Assay Kit Reference: KBBA04S Chromogenic assay for testing Heparins (UFH) in purified systems by measurement of Factor Xa inhibition, in compliance with EP Pharmacopoeia. About the kit: Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity, Recovery rates are between 85 - 115%, Ready to use with a standard protocol with break-apart pre-coated wells, Validated as per US FDA guidelines for Bioassays, Optimized for matrix effects to ensure higher sensitivity, Shelf life: 1 year. The inhibitory effect of Anti-Thrombin III (AT-III) on thrombin (Factor Xa) and other coagulation serine proteases in plasma is increased several thousand-fold by heparin. This inhibition accounts for the anticoagulant effect of heparin. The quantitative determination of heparin levels by the measurement of their Anti-Xa activity is a necessary tool for monitoring treatment efficacy. Unfractionated heparin (UFH) catalyzes both reactions equally. The Factor Xa inhibition test is the most useful assay covering the widest variety of heparin preparations. In the assay, the rate of Factor Xa inhibition is directly proportional to the heparin concentration since both Factor Xa and AT-III are in excess. The residual Factor Xa activity is inversely proportional to the heparin concentration.
KRISHZYME™ Enoxaparin Factor IIa Assay Kit Reference: KBBA03ES Chromogenic assay for testing Enoxaparin in purified systems by measurement of factor IIa inhibition, in compliance with pharmacopoeias (EP/BP) and FDA guidelines About the kit: Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity, Recovery rates are between 85 - 115%, Ready to use with a standard protocol with break-apart pre-coated wells, Validated as per US FDA guidelines for Bioassays, Optimized for matrix effects to ensure higher sensitivity, Shelf life: 1 year. The inhibitory effect of anti-thrombin III (AT-III) on thrombin, factor IIa and other coagulation serine proteases in plasma is increased several thousand-fold by enoxaparin. This inhibition accounts for the anticoagulant effect of enoxaparin. The quantitative determination of enoxaparin levels by the measurement of their anti-IIa activity is a necessary tool for monitoring treatment efficacy. Presence of Enoxaparin catalyzes the reaction between AT lll and α-Thrombin. The factor IIa inhibition test is the most useful assay covering the widest variety of enoxaparin preparations. In the assay, the rate of factor IIa inhibition is directly proportional to the enoxaparin concentration since both factor IIa and AT-III are in excess. The residual factor IIa activity is inversely proportional to the enoxaparin concentration.
KRISHZYME™ Enoxaparin Factor Xa Assay Kit - 200 Tests Reference: KBBA04E Enoxaparin Factor Xa is a chromogenic assay intended for the quantitative determination of enoxaparin in purified solutions by measurement of factor Xa inhibition activity.
KRISHZYME™ Enoxaparin Factor Xa Assay Kit Reference: KBBA04ES Chromogenic assay for testing Enoxaparin in purified systems by measurement of factor Xa inhibition, in compliance with pharmacopoeias (EP/BP) and FDA guidelines About the kit: Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity, Recovery rates are between 85 - 115%, Ready to use with a standard protocol with break-apart pre-coated wells, Validated as per US FDA guidelines for Bioassays, Optimized for matrix effects to ensure higher sensitivity, Shelf life: 1 year. The inhibitory effect of anti-thrombin III (AT-III) on thrombin, factor Xa and other coagulation serine proteases in plasma is increased several thousand-fold by enoxaparin. This inhibition accounts for the anticoagulant effect of enoxaparin. The quantitative determination of enoxaparin levels by the measurement of their anti-Xa activity is a necessary tool for monitoring treatment efficacy. Presence of Enoxaparin catalyzes the reaction between ATlll and Factor Xa. The factor Xa inhibition test is the most useful assay covering the widest variety of enoxaparin preparations. In the assay, the rate of factor Xa inhibition is directly proportional to the enoxaparin concentration since both factor Xa and AT-III are in excess. The residual factor Xa activity is inversely proportional to the enoxaparin concentration.
KRISHZYME™ Dalteparin Factor IIa Assay Kit Reference: KBBA03D Chromogenic assay for testing Dalteparin in purified systems by measurement of factor IIa inhibition activity.
KRISHZYME™ Dalteparin Factor Xa Assay Kit Reference: KBBA04D Chromogenic assay for testing Dalteparin in purified systems by measurement of factor Xa inhibition activity.
KRISHZYME™ Nadroparin Factor IIa Assay Kit Reference: KBBA03N Nadroparin Factor lla is a chromogenic assay intended for the quantitative determination of Nadroparin in purified&solutions by measurement of factor IIa inhibition activity.
KRISHZYME™ Nadroparin Factor Xa Assay Kit Reference: KBBA04N Nadroparin Factor Xa is a chromogenic assay intended for the quantitative determination of Nadroparin in purified&solutions by measurement of factor Xa inhibition activity.
KRISHZYME™ Tinzaparin Factor IIa Assay Kit Reference: KBBA03T Tinzaparin Factor lla is a chromogenic assay intended for the quantitative determination of Tinzaparin in purifiedsolutions by measurement of factor IIa inhibition activity.
KRISHZYME™ Tinzaparin Factor Xa Assay Kit Reference: KBBA04T Tinzaparin Factor Xa is a chromogenic assay intended for the quantitative determination of Tinzaparin in purified solutions by measurement of factor Xa inhibition activity.
KRISHZYME™ Hyaluronidase Enzymatic Assay Kit Reference: KBBA05 Enzymatic Assay for Quantification of Hyaluronidase activity in cell culture supernatant and pharmaceutical preparations Hyaluronidase is a family of enzymes that degrade hyaluronic acid by catalyzing the hydrolysis of hyaluronan, a constituent of the interstitial barrier. Hyaluronidase lowers the viscosity of hyaluronan, thereby increasing tissue permeability. It is, therefore, used in medicine in conjunction with other drugs to speed their dispersion and delivery. About the kit: Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity, Recovery rates are between 85 - 115%, Ready to use with a standard protocol with break-apart pre-coated wells, Validated as per US FDA guidelines for Bioassays, Optimized for matrix effects to ensure higher sensitivity, Shelf life: 1 year. The KRISHZYME™ Hyaluronidase Assay kit uses a two-step turbidimetric reaction to measure hyaluronidase activity by the amount of hyaluronic acid that is hydrolyzed. A stop reagent halts the enzymatic reaction and forms turbidity with any residual hyaluronic acid in the well. The decrease in turbidity at 600 nm is directly proportional to hyaluronidase activity in the sample.