Category: Reagents

Reference: 9002196-10
€0.00 (tax incl.)
A toxin that selectively eliminates pancreatic β-cells in mice, rats, and certain other animals, and is used to model type 1 diabetes in humans
Reference: 9002196-5
€0.00 (tax incl.)
A toxin that selectively eliminates pancreatic β-cells in mice, rats, and certain other animals, and is used to model type 1 diabetes in humans
Reference: 9002215-1
€0.00 (tax incl.)
A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-10
€0.00 (tax incl.)
A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-5
€0.00 (tax incl.)
A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002215-500
€0.00 (tax incl.)
A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell...
Reference: 9002267-10
€0.00 (tax incl.)
A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-100
€0.00 (tax incl.)
A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-250
€0.00 (tax incl.)
A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002267-50
€0.00 (tax incl.)
A positively charged sulfhydryl-specific reagent that reacts with substituted-cysteines; used to provide functional information about relative positions of amino acids within a protein and to probe binding site...
Reference: 9002298-1
€0.00 (tax incl.)
An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-100
€0.00 (tax incl.)
An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-50
€0.00 (tax incl.)
An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002298-500
€0.00 (tax incl.)
An affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand
Reference: 9002314-1
€0.00 (tax incl.)
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-10
€0.00 (tax incl.)
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-5
€0.00 (tax incl.)
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002314-500
€0.00 (tax incl.)
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Reference: 9002339-1
€0.00 (tax incl.)
A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-10
€0.00 (tax incl.)
A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-5
€0.00 (tax incl.)
A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002339-500
€0.00 (tax incl.)
A stereoisomer of IP6; identified in soil samples from Madagascar, New Zealand, and the Falkland Islands and in freshwater sediment from Danish lakes; has been used as a negative control for the stereospecific effects...
Reference: 9002357-1
€0.00 (tax incl.)
An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-10
€0.00 (tax incl.)
An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-25
€0.00 (tax incl.)
An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002357-5
€0.00 (tax incl.)
An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms
Reference: 9002360-1
€0.00 (tax incl.)
A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-10
€0.00 (tax incl.)
A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-5
€0.00 (tax incl.)
A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002360-500
€0.00 (tax incl.)
A tight-binding, allosteric inhibitor of reverse transcriptase that is active against HIV-1 and HIV-2 (both EC50s = 1 nM in vitro)
Reference: 9002394-1
€0.00 (tax incl.)
A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-10
€0.00 (tax incl.)
A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-25
€0.00 (tax incl.)
A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002394-5
€0.00 (tax incl.)
A potent, selective inhibitor of p110δ (IC50 = 15 nM); suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells
Reference: 9002409-10
€0.00 (tax incl.)
An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-100
€0.00 (tax incl.)
An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-25
€0.00 (tax incl.)
An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002409-5
€0.00 (tax incl.)
An antibiotic; has activity against anaerobic bacteria and protozoa; reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions); reduces viable counts of B. fragilis in a rabbit model of infection
Reference: 9002444-1
€0.00 (tax incl.)
A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002444-10
€0.00 (tax incl.)
A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002444-5
€0.00 (tax incl.)
A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 µM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Reference: 9002449-10
€0.00 (tax incl.)
A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-25
€0.00 (tax incl.)
A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-5
€0.00 (tax incl.)
A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002449-50
€0.00 (tax incl.)
A small molecule that stimulates the expression of PGC-1α and downstream genes in skeletal muscle cells, improving glucose utilization and fatty acid oxidation at a concentration of 20 μM; 15 mg/kg/day administered to...
Reference: 9002461-100
€0.00 (tax incl.)
A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via...
Reference: 9002461-250
€0.00 (tax incl.)
A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via...
Reference: 9002461-50
€0.00 (tax incl.)
A bioactive fatty acid; induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively; inhibits C. albicans germination (MIC = 9 µM); inhibits osteogenesis in vitro via...
Reference: 9002495-1
€0.00 (tax incl.)
A sesquiterpene alcohol with diverse biological activities; inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively); reduces the growth of L. infantum and L....
Reference: 9002495-10
€0.00 (tax incl.)
A sesquiterpene alcohol with diverse biological activities; inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively); reduces the growth of L. infantum and L....
Reference: 9002495-25
€0.00 (tax incl.)
A sesquiterpene alcohol with diverse biological activities; inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively); reduces the growth of L. infantum and L....
Reference: 9002495-5
€0.00 (tax incl.)
A sesquiterpene alcohol with diverse biological activities; inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively); reduces the growth of L. infantum and L....
Reference: 9002528-10
€0.00 (tax incl.)
An Hsf1 inhibitor (IC50 = 1.2 μM in a luciferase reporter assay); blocks heat shock-induced Hsp70, Hsp40, and Hsp27 mRNA expression and down-regulates protein expression of the Hsf1 target proteins Hsp70 and Hsp27 in...
Reference: 9002528-5
€0.00 (tax incl.)
An Hsf1 inhibitor (IC50 = 1.2 μM in a luciferase reporter assay); blocks heat shock-induced Hsp70, Hsp40, and Hsp27 mRNA expression and down-regulates protein expression of the Hsf1 target proteins Hsp70 and Hsp27 in...
Reference: 9002543-1
€0.00 (tax incl.)
A thienyl cycloalkanone that is part of the NCI small molecule repository
Reference: 9002543-10
€0.00 (tax incl.)
A thienyl cycloalkanone that is part of the NCI small molecule repository
Reference: 9002543-25
€0.00 (tax incl.)
A thienyl cycloalkanone that is part of the NCI small molecule repository
Reference: 9002543-5
€0.00 (tax incl.)
A thienyl cycloalkanone that is part of the NCI small molecule repository
Reference: 9002699-1
€0.00 (tax incl.)
A quorum sensing signal molecule that controls the expression of many virulence genes as a function of cell population density and can also chelate ferric iron at physiological pH
Reference: 9002699-10
€0.00 (tax incl.)
A quorum sensing signal molecule that controls the expression of many virulence genes as a function of cell population density and can also chelate ferric iron at physiological pH
Reference: 9002699-5
€0.00 (tax incl.)
A quorum sensing signal molecule that controls the expression of many virulence genes as a function of cell population density and can also chelate ferric iron at physiological pH
Reference: 9002775-1
€0.00 (tax incl.)
An inactive metabolite of irinotecan and SN-38; formed by glucuronidation of SN-38 by UGT1A1 and UGT1A7; can be formed by UGT1A1 and UGT1A10
Reference: 9002787-1
€0.00 (tax incl.)
A monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds
Reference: 9002787-10
€0.00 (tax incl.)
A monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds
Reference: 9002787-5
€0.00 (tax incl.)
A monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds
Reference: 9002864-1
€0.00 (tax incl.)
A purine nucleoside with diverse biological activities; inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM, respectively); inhibits the growth of MOLT-4 T cells and MGL-8 B cells at...
Reference: 9002864-10
€0.00 (tax incl.)
A purine nucleoside with diverse biological activities; inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM, respectively); inhibits the growth of MOLT-4 T cells and MGL-8 B cells at...
Reference: 9002864-5
€0.00 (tax incl.)
A purine nucleoside with diverse biological activities; inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 µM, respectively); inhibits the growth of MOLT-4 T cells and MGL-8 B cells at...
Reference: 9002910-1
€0.00 (tax incl.)
An inhibitor of BET family proteins; binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively
Reference: 9002910-10
€0.00 (tax incl.)
An inhibitor of BET family proteins; binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively
Reference: 9002910-25
€0.00 (tax incl.)
An inhibitor of BET family proteins; binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively
Reference: 9002910-5
€0.00 (tax incl.)
An inhibitor of BET family proteins; binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively
Reference: 9002936-1
€0.00 (tax incl.)
A Smo antagonist (IC50 = 5 nM); attenuates leukemia stem cell self-renewal and cell cycle progression in primary AML cells and in an in vivo Drosophila model
Reference: 9002936-10
€0.00 (tax incl.)
A Smo antagonist (IC50 = 5 nM); attenuates leukemia stem cell self-renewal and cell cycle progression in primary AML cells and in an in vivo Drosophila model
Reference: 9002936-25
€0.00 (tax incl.)
A Smo antagonist (IC50 = 5 nM); attenuates leukemia stem cell self-renewal and cell cycle progression in primary AML cells and in an in vivo Drosophila model
Reference: 9002936-5
€0.00 (tax incl.)
A Smo antagonist (IC50 = 5 nM); attenuates leukemia stem cell self-renewal and cell cycle progression in primary AML cells and in an in vivo Drosophila model
Reference: 9002951-1
€0.00 (tax incl.)
A G3BP2 inhibitor; reduces tumor-initiating cells in a mouse xenograft model of breast cancer; diminishes mammosphere formation in MDA-MB-453 cells and a patient-derived xenograft cell line
Reference: 9002951-5
€0.00 (tax incl.)
A G3BP2 inhibitor; reduces tumor-initiating cells in a mouse xenograft model of breast cancer; diminishes mammosphere formation in MDA-MB-453 cells and a patient-derived xenograft cell line
Reference: 9002951-500
€0.00 (tax incl.)
A G3BP2 inhibitor; reduces tumor-initiating cells in a mouse xenograft model of breast cancer; diminishes mammosphere formation in MDA-MB-453 cells and a patient-derived xenograft cell line
Reference: 9002958-1
€0.00 (tax incl.)
A ribonucleoside analog with antiviral activity; inhibits replication of SARS-CoV in Vero 76 cells, MERS-CoV in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively); reduces viral...
Reference: 9002958-10
€0.00 (tax incl.)
A ribonucleoside analog with antiviral activity; inhibits replication of SARS-CoV in Vero 76 cells, MERS-CoV in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively); reduces viral...
Reference: 9002958-25
€0.00 (tax incl.)
A ribonucleoside analog with antiviral activity; inhibits replication of SARS-CoV in Vero 76 cells, MERS-CoV in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively); reduces viral...
Reference: 9002958-5
€0.00 (tax incl.)
A ribonucleoside analog with antiviral activity; inhibits replication of SARS-CoV in Vero 76 cells, MERS-CoV in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively); reduces viral...
Reference: 9003061-1
€0.00 (tax incl.)
An electron transport inhibitor in plants; competitively inhibits plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM); inhibits electron flow from water to NADP or methylviologen by 50 and...
Reference: 9003061-10
€0.00 (tax incl.)
An electron transport inhibitor in plants; competitively inhibits plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM); inhibits electron flow from water to NADP or methylviologen by 50 and...
Reference: 9003061-25
€0.00 (tax incl.)
An electron transport inhibitor in plants; competitively inhibits plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM); inhibits electron flow from water to NADP or methylviologen by 50 and...
Reference: 9003061-5
€0.00 (tax incl.)
An electron transport inhibitor in plants; competitively inhibits plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM); inhibits electron flow from water to NADP or methylviologen by 50 and...
Reference: 9003088-1
€0.00 (tax incl.)
A positive-gating modulator of IKCa1/KCa3.1 channels (EC50 = 109 nM); selective for KCa3.1 over KCa2.1, KCa2.2 and KCa2.3 (EC50s = 8,700, 6,800, and 4,400 nM, respectively), KCa1.1 as well as voltage-gated potassium...
Reference: 9003088-10
€0.00 (tax incl.)
A positive-gating modulator of IKCa1/KCa3.1 channels (EC50 = 109 nM); selective for KCa3.1 over KCa2.1, KCa2.2 and KCa2.3 (EC50s = 8,700, 6,800, and 4,400 nM, respectively), KCa1.1 as well as voltage-gated potassium...

Menu

Settings